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特发性左心室心动过速机制的见解:一例病例报告及文献综述。

Insights into the mechanism of idiopathic left ventricular tachycardia: a case report and literature review.

作者信息

Puie Paul, Cismaru Gabriel, Muresan Lucian, Rosu Radu, Puiu Mihai, Andronache Marius, Gusetu Gabriel, Matuz Roxana, Mircea Petru-Adrian, Pop Dana, Zdrenghea Dumitru

机构信息

Department of Cardiology, Rehabilitation Hospital, "Iuliu Hatieganu" University of Medicine and Pharmacy, 46-50 Viilor Street, 400347, Cluj-Napoca, Romania.

Department of Electrophysiology, Institut Lorrain du Coeur et des Vaisseaux «Louis Mathieu», CHU de Nancy, Cluj-Napoca, France.

出版信息

Eur J Med Res. 2015 Sep 17;20(1):77. doi: 10.1186/s40001-015-0156-y.

Abstract

Left ventricular posterior fascicular tachycardia (LVPFT) is an idiopathic form of VT characterized by right bundle branch block morphology and left axis deviation. The mechanism of LPFVT is thought to be localized reentry close to the posterior fascicle. We present the case of a 24-year-old medical student who was admitted to the emergency department complaining of palpitations. The ECG showed an aspect suggestive of LVPFT. Vagal maneuvers, adenosine and i.v. Metoprolol were ineffective in terminating the arrhythmia. Conversion to sinus rhythm was obtained 10 h later, with i.v Amiodarone. The ECG in sinus rhythm showed left posterior fascicular block. Because antiarrhythmic drugs were not desired by the patient, VT ablation was proposed. The electrophysiological study identified the mechanism of arrhythmia to be reentry using the slowly conducting verapamil-sensitive fibers as the antegrade limb and the posterior fascicle as the retrograde limb. Radiofrequency applications near the posterior fascicle, in the lower half of the interventricular septum, at the junction of the two proximal thirds with the distal third interrupted the tachycardia and made it non-inducible at programmed stimulation. The case is unusual as the patient had a left posterior fascicular block during sinus rhythm before ablation. This demonstrates that the reentry circuit of VT does not need antegrade conduction through the posterior fascicle for perpetuation.

摘要

左心室后分支性心动过速(LVPFT)是室性心动过速(VT)的一种特发性形式,其特征为右束支传导阻滞形态和电轴左偏。LPFVT的机制被认为是靠近后分支的局部折返。我们报告一例24岁医科学生的病例,该患者因心悸入住急诊科。心电图显示有提示LVPFT的表现。迷走神经刺激、腺苷和静脉注射美托洛尔均未能终止心律失常。10小时后静脉注射胺碘酮使心律转为窦性。窦性心律时的心电图显示左后分支阻滞。由于患者不希望使用抗心律失常药物,故建议进行室性心动过速消融治疗。电生理研究确定心律失常的机制为折返,其顺行支为传导缓慢的维拉帕米敏感纤维,逆行支为后分支。在室间隔下半部靠近后分支处、在两个近端三分之一与远端三分之一交界处进行射频消融,打断了心动过速,并使其在程序刺激下不能被诱发。该病例不同寻常之处在于患者在消融术前窦性心律时就存在左后分支阻滞。这表明室性心动过速的折返环并不需要通过后分支进行顺向传导来维持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8b/4573491/ba1ab2da8e03/40001_2015_156_Fig1_HTML.jpg

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