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[束支性室性心动过速]

[Fascicular ventricular tachycardia].

作者信息

Chiarandà G, Di Guardo G, Gulizia M, Lazzaro A, Regolo T

机构信息

Unità Operativa di Cardiologia, Ospedale E. Muscatello, Augusta, SR.

出版信息

Ital Heart J Suppl. 2001 Nov;2(11):1181-6.

PMID:11775409
Abstract

Fascicular tachycardia is an uncommon idiopathic ventricular tachycardia, originating from the left ventricle; it usually occurs in young male patients, with a high prevalence in south-east Asiatic people. Electrocardiographic aspects of this unique ventricular tachycardia (right bundle branch block morphology and left or right-axis deviation, with a moderate QRS widening) and verapamil sensitivity make it often difficult the differential diagnosis with other forms of supraventricular tachycardia. Reentry is believed to be the operative mechanism of fascicular tachycardia, with the reentrant circuit located in the Purkinje network, in the region of the left posterior or anterior fascicle. The slow conduction zone participating in the reentry circuit, made up of partially depolarized Purkinje fibers, seems to be located in a relatively wide area, from the basal to the apical left interventricular septum. Intravenous verapamil is elective in acute treatment; however oral verapamil shows poor efficacy in preventing tachycardia relapses. Ablative approach is very effective; success is achieved in approximately 90% of patients, with rare complications. Recently diastolic potentials during fascicular tachycardia have been reported and these findings have given rise to new electrophysiological hypotheses and new indications about the successful ablation site.

摘要

分支性心动过速是一种罕见的特发性室性心动过速,起源于左心室;通常发生于年轻男性患者,在东南亚人群中患病率较高。这种独特室性心动过速的心电图表现(右束支传导阻滞形态及左或右轴偏移,QRS波轻度增宽)以及对维拉帕米的敏感性使得其与其他形式的室上性心动过速的鉴别诊断常常存在困难。折返被认为是分支性心动过速的发病机制,折返环位于左后或前分支区域的浦肯野纤维网中。参与折返环的缓慢传导区由部分去极化的浦肯野纤维组成,似乎位于从心底到心尖的左室间隔相对较宽的区域。静脉注射维拉帕米是急性治疗的首选;然而口服维拉帕米在预防心动过速复发方面疗效不佳。消融治疗非常有效;约90%的患者可获得成功,并发症罕见。最近有报道称分支性心动过速期间存在舒张期电位,这些发现引发了关于成功消融部位的新的电生理假说和新的指征。

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引用本文的文献

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Magnetic Resonance Features of a Recent Catheter Ablation of Left Posterior Fascicular Ventricular Tachycardia.近期左后分支室性心动过速导管消融术的磁共振成像特征
Cureus. 2021 Jul 22;13(7):e16555. doi: 10.7759/cureus.16555. eCollection 2021 Jul.
2
Insights into the mechanism of idiopathic left ventricular tachycardia: a case report and literature review.特发性左心室心动过速机制的见解:一例病例报告及文献综述。
Eur J Med Res. 2015 Sep 17;20(1):77. doi: 10.1186/s40001-015-0156-y.
3
Idiopathic fascicular ventricular tachycardia.特发性分支性室性心动过速
Indian Pacing Electrophysiol J. 2004 Jul 1;4(3):98-103.