Jeon H J, Kim B M, Kim D J, Park K Y, Kim J W, Kim D I
From the Department of Neurosurgery (H.J.J.), Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea.
Departments of Radiology (B.M.K., D.J.K., J.W.K., D.I.K.) bmoon21@hanmail.
AJNR Am J Neuroradiol. 2016 Feb;37(2):311-6. doi: 10.3174/ajnr.A4526. Epub 2015 Sep 17.
Coiling of complex aneurysms is still difficult even with current adjuvant techniques. This study sought to evaluate the safety and effectiveness of a combination of multicatheter plus stent or balloon for the treatment of complex aneurysms.
All complex aneurysms that underwent coiling with the combination technique were identified from prospectively maintained neurointerventional data bases. "Complex aneurysm" was defined as a wide-neck aneurysm with branch incorporation into or a deep lobulation of the sac. The clinical and angiographic outcomes were retrospectively analyzed.
Sixty-two complex aneurysms (12 ruptured, 50 unruptured) in 62 patients (mean age, 57 years; male/female ratio, 12:50) were treated with a combination technique by using a multicatheter plus stent (n = 42, 3 ruptured) or balloon (n = 20, 9 ruptured). Treatment-related morbidity (grade 3 hemiparesis) occurred in 1 patient (1.6%). Except for 1 patient who had treatment-related morbidity, none of the other patients with unruptured aneurysms developed new neurologic symptoms at discharge. Nine of the 12 patients with ruptured aneurysms had good outcomes (Glasgow Outcome Score, 4 or 5) at the latest follow-up (mean, 32 months; range, 6-72 months), and 1 patient died from an initial SAH. Posttreatment control angiograms revealed complete occlusion in 27, neck remnant in 34, and incomplete occlusion in 1 aneurysm. At least 1 follow-up catheter or MR angiogram was available in 80.6% (n = 50) (mean, 21 months; range, 6-65 months). There were 4 minor and 3 major recurrences (14.0%).
In this case series, the combination technique by using multicatheter plus stent or balloon seemed safe and effective for the treatment of complex aneurysms.
即便采用当前的辅助技术,复杂动脉瘤的栓塞治疗仍颇具难度。本研究旨在评估多导管联合支架或球囊治疗复杂动脉瘤的安全性与有效性。
从前瞻性维护的神经介入数据库中识别出所有采用联合技术进行栓塞治疗的复杂动脉瘤。“复杂动脉瘤”定义为伴有分支卷入或瘤囊深分叶的宽颈动脉瘤。对临床及血管造影结果进行回顾性分析。
62例患者(平均年龄57岁;男女比例为12:50)的62个复杂动脉瘤(12个破裂,50个未破裂)采用多导管联合支架(n = 42,3个破裂)或球囊(n = 20,9个破裂)的联合技术进行治疗。1例患者(1.6%)出现与治疗相关的并发症(3级偏瘫)。除1例出现与治疗相关并发症的患者外,其他未破裂动脉瘤患者在出院时均未出现新的神经症状。12例破裂动脉瘤患者中,9例在最近一次随访时(平均32个月;范围6 - 72个月)预后良好(格拉斯哥预后评分4或5),1例患者死于初始蛛网膜下腔出血。治疗后造影显示27个完全闭塞,34个有颈部残留,1个不完全闭塞。80.6%(n = 50)的患者有至少1次随访导管造影或磁共振血管造影(平均21个月;范围6 - 65个月)。有4例轻微复发和3例严重复发(14.0%)。
在本病例系列中,多导管联合支架或球囊的联合技术治疗复杂动脉瘤似乎安全有效。