Wolff H
Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland.
Internist (Berl). 2015 Oct;56(10):1196-208. doi: 10.1007/s00108-015-3763-3.
Alopecia is the term used to describe hairless areas of the scalp. They can follow a specific pattern, be diffuse or circumscript. Androgenetic alopecia (AGA) follows a pattern: in men thinning of temples and vertex up to total baldness; in women thinning of the midline or parietal area.
Lack of iron or cytostatic drugs cause diffuse alopecia, while in autoimmune diseases such as alopecia areata or lichen planus bizarre shapes of hairless areas are observed.
For therapy, the following medications are used: topical minoxidil solution for AGA of men and women; systemic finasteride 1 mg for men with AGA; topical diphencyprone immunotherapy for alopecia areata; systemic antimycotic agents for tinea capitis; antibiotics such as clindamycin and rifampicin for folliculitis decalvans; systemic corticosteroids and isotretinoin for folliculitis et perifolliculitis capitis abscedens et suffodiens; topical corticosteroids for lichen planus and Kossard's frontal fibrosing alopecia.
脱发是用于描述头皮无毛区域的术语。它们可呈现特定模式,可为弥漫性或局限性。雄激素性脱发(AGA)呈特定模式:男性表现为颞部和头顶毛发稀疏直至完全秃发;女性表现为中线或顶叶区域毛发稀疏。
缺铁或使用细胞毒性药物可导致弥漫性脱发,而在斑秃或扁平苔藓等自身免疫性疾病中,可观察到无毛区域呈现怪异形状。
治疗时使用以下药物:男女AGA均使用外用米诺地尔溶液;男性AGA使用系统非那雄胺1毫克;斑秃使用外用二苯环丙烯酮免疫疗法;头癣使用系统抗真菌药;脱发性毛囊炎使用克林霉素和利福平等抗生素;脓肿性穿掘性头部毛囊周围炎使用系统皮质类固醇和异维A酸;扁平苔藓和科萨德额部纤维性脱发使用外用皮质类固醇。