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经皮电神经刺激对貌似健康个体的血流动力学影响:一项荟萃分析的系统评价

Hemodynamic Effects Induced by Transcutaneous Electrical Nerve Stimulation in Apparently Healthy Individuals: A Systematic Review With Meta-Analysis.

作者信息

Campos Filippe V, Neves Laura M, Da Silva Vinicius Z, Cipriano Graziella F, Chiappa Gaspar R, Cahalin Lawrence, Arena Ross, Cipriano Gerson

机构信息

Health Sciences and Technologies PhD Program, Department of Physical Therapy, University of Brasilia, Brasilia, Brazil; Cardiac Rehabilitation Ambulatory, Armed Forces Hospital, Brasilia, Brazil.

Health Sciences and Technologies PhD Program, Department of Physical Therapy, University of Brasilia, Brasilia, Brazil; University of Para, Belém, Brazil.

出版信息

Arch Phys Med Rehabil. 2016 May;97(5):826-35. doi: 10.1016/j.apmr.2015.08.433. Epub 2015 Sep 15.

Abstract

OBJECTIVE

To determine the immediate effects of transcutaneous electrical nerve stimulation (TENS) on heart rate, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in apparently healthy adults (age ≥18y).

DATA SOURCES

The Cochrane Library (online version 2014), PubMed (1962-2014), EMBASE (1980-2014), and LILACS (1980-2014) electronic databases were searched.

STUDY SELECTION

Randomized controlled trials were included when TENS was administered noninvasively with surface electrodes during rest, and the effect of TENS was compared with that of control or placebo TENS. A sensitive search strategy for identifying randomized controlled trials was used by 2 independent reviewers. The initial search led to the identification of 432 studies, of which 5 articles met the eligibility criteria.

DATA EXTRACTION

Two independent reviewers extracted data from the selected studies. Quality was evaluated using the PEDro scale. Mean differences or standardized mean differences in outcomes were calculated.

DATA SYNTHESIS

Five eligible articles involved a total of 142 apparently healthy individuals. Four studies used high-frequency TENS and 3 used low-frequency TENS and evaluated the effect on SBP. Three studies using high-frequency TENS and 2 using low-frequency TENS evaluated the effect on DBP. Three studies using high-frequency TENS and 1 study using low-frequency TENS evaluated the effect on heart rate. A statistically significant reduction in SBP (-3.00mmHg; 95% confidence interval [CI], -5.02 to -0.98; P=.004) was found using low-frequency TENS. A statistically significant reduction in DBP (-1.04mmHg; 95% CI, -2.77 to -0.03; I(2)=61%; P=.04) and in heart rate (-2.55beats/min; 95% CI, -4.31 to -0.78; I(2)=86%; P=.005]) was found using both frequencies. The median value on the PEDro scale was 7 (range, 4-8).

CONCLUSIONS

TENS seems to promote a discrete reduction in SBP, DBP, and heart rate in apparently healthy individuals.

摘要

目的

确定经皮电刺激神经疗法(TENS)对明显健康的成年人(年龄≥18岁)心率、收缩压(SBP)和舒张压(DBP)的即时影响。

数据来源

检索了考科蓝图书馆(2014年在线版)、PubMed(1962 - 2014年)、EMBASE(1980 - 2014年)和LILACS(1980 - 2014年)电子数据库。

研究选择

纳入在静息状态下使用表面电极无创给予TENS,并将TENS的效果与对照或安慰剂TENS的效果进行比较的随机对照试验。由2名独立评审员采用敏感的检索策略来识别随机对照试验。初步检索共识别出432项研究,其中5篇文章符合纳入标准。

数据提取

2名独立评审员从选定的研究中提取数据。使用PEDro量表评估质量。计算结局的平均差或标准化平均差。

数据综合

5篇符合条件的文章共涉及142名明显健康的个体。4项研究使用高频TENS,3项研究使用低频TENS并评估对SBP的影响。3项使用高频TENS的研究和2项使用低频TENS的研究评估对DBP的影响。3项使用高频TENS的研究和1项使用低频TENS的研究评估对心率的影响。使用低频TENS时发现SBP有统计学显著降低(-3.00mmHg;95%置信区间[CI],-5.02至-0.98;P = 0.004)。两种频率使用时均发现DBP(-1.04mmHg;95% CI,-2.77至-0.03;I² = 61%;P = 0.04)和心率(-2.55次/分钟;95% CI,-4.31至-0.78;I² = 86%;P = 0.005)有统计学显著降低。PEDro量表的中位数为7(范围4 - 8)。

结论

TENS似乎能使明显健康个体的SBP、DBP和心率有一定程度的降低。

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