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胸段食管憩室:15年微创手术治疗经验

Thoracic Esophageal Diverticula: A 15-Year Experience of Minimally Invasive Surgical Management.

作者信息

Macke Ryan A, Luketich James D, Pennathur Arjun, Bianco Valentino, Awais Omar, Gooding William E, Christie Neil A, Schuchert Matthew J, Nason Katie S, Levy Ryan M

机构信息

Department of Cardiothoracic Surgery, Division of Thoracic and Foregut Surgery, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Department of Cardiothoracic Surgery, Division of Thoracic and Foregut Surgery, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

出版信息

Ann Thorac Surg. 2015 Nov;100(5):1795-802. doi: 10.1016/j.athoracsur.2015.04.122. Epub 2015 Sep 19.

Abstract

BACKGROUND

Thoracic esophageal diverticula are uncommon, and controversies exist regarding their management. The objective of this study was to evaluate the outcomes of a relatively large cohort of patients with thoracic esophageal diverticula treated with minimally invasive surgical techniques.

METHODS

We conducted a retrospective review of patients who underwent minimally invasive surgical treatment for symptomatic esophageal diverticula during a 15-year period. The primary end point was 30-day mortality. In addition, we evaluated the morbidity, improvement in dysphagia (score: 1, best to 5, worst), and quality of life (Gastroesophageal Reflux Disease-Health-Related Quality of Life score: 0, best to 50, most symptoms).

RESULTS

Fifty-seven patients underwent minimally invasive surgical treatment of symptomatic thoracic esophageal diverticula. The most common symptom was dysphagia (45 of 57; 79%). A motility disorder or distal mechanical obstruction was identified in 49 patients (86%). Approaches used included video-assisted thoracoscopic surgery (n = 33), laparoscopy (n = 18), and combined video-assisted thoracoscopic surgery and laparoscopy (n = 6). The most common procedure performed was diverticulectomy and myotomy (47 of 57 patients; 82.5%). The 30-day mortality was 0%. There were 4 patients (7%) with postoperative leaks requiring reoperation. During follow-up, the median dysphagia score improved from 3 to 1 (p < 0.001). The median Gastroesophageal Reflux Disease-Health-Related Quality of Life score after surgery was 5 (excellent).

CONCLUSIONS

A minimally invasive surgical approach for the management of thoracic esophageal diverticula is safe and effective during intermediate-term follow-up when performed by surgeons experienced in esophageal surgery and minimally invasive techniques. Further follow-up is required to assess the durability of these results. The optimal approach and procedures performed should be determined on an individualized basis after a thorough investigation.

摘要

背景

胸段食管憩室并不常见,其治疗方法存在争议。本研究的目的是评估采用微创外科技术治疗的相对较大队列的胸段食管憩室患者的治疗效果。

方法

我们对15年间因有症状的食管憩室接受微创外科治疗的患者进行了回顾性研究。主要终点是30天死亡率。此外,我们评估了发病率、吞咽困难的改善情况(评分:1为最佳,5为最差)以及生活质量(胃食管反流病健康相关生活质量评分:0为最佳,50为症状最严重)。

结果

57例患者接受了有症状胸段食管憩室的微创外科治疗。最常见的症状是吞咽困难(57例中的45例;79%)。49例患者(86%)被发现存在动力障碍或远端机械性梗阻。采用的手术方式包括电视辅助胸腔镜手术(n = 33)、腹腔镜手术(n = 18)以及电视辅助胸腔镜手术与腹腔镜手术联合(n = 6)。最常进行的手术是憩室切除术和肌切开术(57例患者中的47例;82.5%)。30天死亡率为0%。有4例患者(7%)术后发生漏,需要再次手术。在随访期间,吞咽困难评分中位数从3改善至1(p < 0.001)。术后胃食管反流病健康相关生活质量评分中位数为5(极佳)。

结论

对于胸段食管憩室的治疗,由有食管手术和微创技术经验的外科医生进行中期随访时,微创外科手术方法是安全有效的。需要进一步随访以评估这些结果的持久性。应在全面检查后根据个体情况确定最佳手术方式和操作。

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