肠球菌血培养单阳性与多阳性患者的结局比较：感染还是假象？
Comparison of outcomes between patients with single versus multiple positive blood cultures for Enterococcus: Infection versus illusion?
作者信息
Claeys Kimberly C, Zasowski Evan J, Lagnf Abdalhamid M, Rybak Michael J
机构信息
Anti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI.
Anti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI; School of Medicine, Wayne State University, Detroit, MI.
出版信息
Am J Infect Control. 2016 Jan 1;44(1):47-9. doi: 10.1016/j.ajic.2015.08.002. Epub 2015 Sep 19.
Enterococci represent one of the most common causative pathogens of bloodstream infections (BSIs). There is debate in the literature regarding the clinical importance of single versus multiple positive blood cultures for Enterococci. This single-center retrospective study found that patients with multiple positive blood cultures experienced increased inpatient mortality and a shorter median survival. Additionally, BSIs >6.7 days resulted in approximately 20% increased mortality. These results are preliminary and require further exploration.
肠球菌是血流感染（BSIs）最常见的致病病原体之一。关于肠球菌单次血培养阳性与多次血培养阳性的临床重要性，文献中存在争议。这项单中心回顾性研究发现，多次血培养阳性的患者住院死亡率增加，中位生存期缩短。此外，血行感染超过6.7天会导致死亡率增加约20%。这些结果是初步的，需要进一步探索。
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