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种族差异是否会影响前交叉韧带重建患者的术前特征和术中发现?

Does Racial Variation Influence Preoperative Characteristics and Intraoperative Findings in Patients Undergoing Anterior Cruciate Ligament Reconstruction?

作者信息

Navarro Ronald A, Inacio Maria C S, Maletis Gregory B

机构信息

Department of Orthopaedic Surgery, Kaiser Permanente South Bay, Harbor City, California, USA

Surgical Outcomes & Analysis Unit, Southern California Permanente Medical Group (SCPMG) Clinical Analysis Department, San Diego, California, USA.

出版信息

Am J Sports Med. 2015 Dec;43(12):2959-65. doi: 10.1177/0363546515603053. Epub 2015 Sep 21.

Abstract

BACKGROUND

A limited number of large multiethnic cohorts of patients undergoing anterior cruciate ligament reconstruction (ACLR) exist; therefore, little is known about racial differences in preoperative and intraoperative characteristics of patients undergoing this procedure.

PURPOSE

To evaluate preoperative patient, surgeon, and hospital characteristics and intraoperative findings associated with various patient races undergoing ACLR.

STUDY DESIGN

Cohort study; Level of evidence, 3.

METHODS

A cross-sectional study of patients undergoing primary ACLR (performed between January 1, 2008 and September 30, 2012) was conducted. The Kaiser Permanente ACLR Registry was used to identify the cases and variables for the study. The variables of age, sex, time from injury to surgery, body mass index, sport at the time of injury, concomitant injury (menisci, cartilage, other ligament), surgeon training, and surgeon and site volumes were evaluated. Race was categorized into white (reference), Hispanic, Asian, and black. Polychotomous regression models were employed. Odds ratios (ORs) and 95% CIs are provided.

RESULTS

A total of 14,278 ACLRs were evaluated; there were 7401 (51.8%) ACLRs performed on white, 3912 (27.4%) on Hispanic, 1894 (13.3%) on Asian, and 1071 (7.5%) on black patients. Men predominated overall as well as in each of the race categories. Compared with white patients, after adjusting for all covariates, Asian (OR, 1.24; 95% CI, 1.10-1.40) and Hispanic (OR, 1.52; 95% CI, 1.39-1.67) patients undergoing ACLR were more likely to be male than female, and black patients were more likely to be female (OR, 0.69; 95% CI, 0.60-0.80). All racial groups tended to undergo ACLR in younger age bands compared with white patients, with black patients having the highest odds of being < 17 years (OR, 2.74; 95% CI, 2.23-3.37) and 17 to 24 years of age (OR, 2.28; 95% CI, 1.94-2.68) compared with being ≥ 25 years. Asian patients were more likely injured playing basketball (OR, 4.31; 95% CI, 3.67-5.06), black patients during football (OR, 3.48; 95% CI, 2.73-4.45) and basketball (OR, 5.52; 95% CI, 4.49-6.78), and Hispanic patients during soccer (OR, 3.09; 95% CI, 2.75-3.48). Hispanic patients had a higher likelihood of having both menisci injured at the time of surgery (OR, 1.31; 95% CI, 1.16-1.49) as well as the lateral meniscus (OR, 1.31; 95% CI, 1.17-1.47). Asian patients had a lower likelihood of cartilage injuries (OR, 0.78; 95% CI, 0.68-0.88). Sports medicine fellowship-trained surgeons were more likely to have operated on black (OR, 1.27; 95% CI, 1.07-1.51) and Hispanic (OR, 1.16; 95% CI, 1.04-1.29) patients.

CONCLUSION

In this large representative sample of patients undergoing ACLR in the United States, 48.2% of the cohort was nonwhite, and racial variations in sex, age, sport at injury, and intraoperative findings at ACLR were identified. Understanding the differences in ACL injury presentation and concomitant injuries by race can be useful in helping tailor the development of an ACL injury prevention program, during the informed consent process, and in the arthroscopic portion of the procedure according to patient race-specific characteristics.

摘要

背景

进行前交叉韧带重建(ACLR)的大型多民族患者队列数量有限;因此,对于接受该手术患者的术前和术中特征的种族差异了解甚少。

目的

评估接受ACLR的不同种族患者的术前患者、外科医生和医院特征以及术中发现。

研究设计

队列研究;证据等级,3级。

方法

对2008年1月1日至2012年9月30日期间接受初次ACLR的患者进行横断面研究。使用凯撒医疗ACLR登记处来确定研究的病例和变量。评估了年龄、性别、受伤至手术的时间、体重指数、受伤时的运动项目、合并损伤(半月板、软骨、其他韧带)、外科医生培训情况以及外科医生和手术量。种族分为白人(参照组)、西班牙裔、亚裔和黑人。采用多分类回归模型。提供了比值比(OR)和95%可信区间(CI)。

结果

共评估了14278例ACLR;其中7401例(51.8%)为白人患者接受的ACLR,3912例(27.4%)为西班牙裔患者,1894例(13.3%)为亚裔患者,1071例(7.5%)为黑人患者。总体上男性占主导,各种族类别中也是如此。与白人患者相比,在调整所有协变量后,接受ACLR的亚裔(OR,1.24;95%CI,1.10 - 1.40)和西班牙裔(OR,1.52;95%CI,1.39 - 1.67)患者男性多于女性,而黑人患者女性多于男性(OR,0.69;95%CI,0.60 - 0.80)。与白人患者相比,所有种族组接受ACLR的年龄都较小,黑人患者年龄<17岁(OR,2.74;95%CI,2.23 - 3.37)和17至24岁(OR,2.28;95%CI,1.94 - 2.68)的可能性高于年龄≥25岁的可能性。亚裔患者打篮球受伤的可能性更大(OR,4.31;95%CI,3.67 - 5.06),黑人患者在踢足球(OR,3.48;95%CI,2.73 - 4.45)和打篮球时受伤(OR,5.52;95%CI,4.49 - 6.78),西班牙裔患者在踢足球时受伤(OR,3.09;95%CI,2.75 - 3.48)。西班牙裔患者手术时半月板双侧损伤(OR,1.31;95%CI,1.16 - 1.49)以及外侧半月板损伤(OR,1.31;95%CI,1.17 - 1.47)的可能性更高。亚裔患者软骨损伤的可能性较低(OR,0.78;95%CI,0.68 - 0.88)。接受运动医学专科培训的外科医生更有可能为黑人(OR,1.27;95%CI,1.07 - 1.51)和西班牙裔(OR,1.16;95%CI,1.04 - 1.29)患者进行手术。

结论

在美国接受ACLR的这一大型代表性患者样本中,48.2%的队列是非白人,并且在性别、年龄、受伤时的运动项目以及ACLR术中发现方面存在种族差异。了解不同种族ACL损伤表现和合并损伤的差异有助于制定ACL损伤预防计划、在知情同意过程中以及根据患者种族特异性特征在手术的关节镜部分进行调整。

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