Kim Jin, Choi Jae Young
a Department of Otorhinolaryngology , Inje University College of Medicine , Goyang-si , Republic of Korea and.
b Department of Otorhinolaryngology , Yonsei University College of Medicine , Seoul , Republic of Korea.
Acta Otolaryngol. 2016;136(1):100-5. doi: 10.3109/00016489.2015.1083121. Epub 2015 Sep 23.
The drug regimen plus electrical stimulation was more effective in treating Bell's palsy than the conventional drug treatment alone. The effectiveness of such a sub-threshold, continuous, low frequency electrical stimulation suggests a new therapeutic approach to accelerate nerve regeneration and improve functional recovery after injury.
The purpose of this study was to determine whether sub-threshold, continuous electrical stimulation at 20 Hz facilitates functional recovery of patients with Bell's palsy.
The authors performed a prospective randomized study that included 60 patients with mild-to-moderate grade Bell's palsy (HB grade ≤4, SB grade ≥40), to evaluate the effect of developed electrical stimulation on the resolution of symptoms. Thirty patients were treated with prednisolone or/and acyclovir plus electrical stimulation within 7 days of the onset of symptoms. The other 30 patients were treated with only prednisolone or/and acyclovir as a control group.
The overall rate of patient recovery among those treated with prednisolone or/and acyclovir plus electrical stimulation (96%) was significantly better (p < 0.05) than the rate among those treated with only prednisolone or/and acyclovir (88%).
药物疗法加电刺激治疗贝尔面瘫比单纯传统药物治疗更有效。这种阈下、连续、低频电刺激的有效性提示了一种加速神经再生和改善损伤后功能恢复的新治疗方法。
本研究旨在确定20赫兹的阈下连续电刺激是否有助于贝尔面瘫患者的功能恢复。
作者进行了一项前瞻性随机研究，纳入60例轻至中度贝尔面瘫患者（HB分级≤4，SB分级≥40），以评估所研发的电刺激对症状缓解的效果。30例患者在症状发作7天内接受泼尼松龙或/和阿昔洛韦加电刺激治疗。另外30例患者仅接受泼尼松龙或/和阿昔洛韦治疗作为对照组。
接受泼尼松龙或/和阿昔洛韦加电刺激治疗的患者总体恢复率（96%）显著高于仅接受泼尼松龙或/和阿昔洛韦治疗的患者（88%）（p＜0.05）。
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