Tuncel Altug, Balci Melih, Postaci Aysun, Aslan Yilmaz, Atan Ali
Third Department of Urology, Ministry of Health, Ankara Numune Research and Training Hospital, Ankara, Turkey.
Second Department of Anaesthesiology, Ministry of Health, Ankara Numune Research and Training Hospital, Ankara, Turkey.
Int Braz J Urol. 2015 Jul-Aug;41(4):669-75. doi: 10.1590/S1677-5538.IBJU.2013.0238.
We compared the effects of local levobupivacaine infiltration, intravenous paracetamol, intravenous lornoxicam treatments on postoperative analgesia in patients submitted to transperitoneal laparoscopic renal and adrenal surgery.
Sixty adult patients 26 and 70 years who underwent laparoscopic renal and adrenal surgery were randomized into three groups with 20 patients each: Group 1 received local 20 mL of levobupivacaine 0.25% infiltration to the trocar incisions before skin closure. In group 2, 1g paracetamol was given to the patients intravenously 30 minutes before extubation and 5 g paracetamol was given intravenously in the 24 postoperative period. In group 3, 8 mg lornoxicam i.v. was given 30 minutes before extubation and 8 mg lornoxicam i.v. was given in the 24 postoperative period. In the postoperative period, pain scores, cumulative tramadol, and additional pethidine consumption were evaluated.
Postoperative pain scores significantly reduced in each group (p < 0.05). Although pain levels of the groups were not significantly different at 1, 2, 4, 8, 12 and 24 hours postoperatively, cumulative tramadol consumptions were higher in group 1 than the others. (Group 1 = 370.6 ± 121.6 mg, Group 2: 220.9 ± 92.5mg, Group 3 = 240.7 ± 100.4 mg.) (p < 0.005). The average dose of pethidine administered was significantly lower in groups 2 and 3 compared with group 1 (Group 1: 145 mg, Group 2: 100mg, Group 3: 100mg) (p = 0.024).
Levobupivacaine treated group required significantly more intravenous tramadol when compared with paracetamol and lornoxicam groups in patients submitted to transperitoneal laparoscopic renal and adrenal surgery.
我们比较了局部左旋布比卡因浸润、静脉注射对乙酰氨基酚、静脉注射氯诺昔康治疗对接受经腹腹腔镜肾脏和肾上腺手术患者术后镇痛的效果。
60例年龄在26至70岁之间接受腹腔镜肾脏和肾上腺手术的成年患者被随机分为三组,每组20例:第1组在皮肤缝合前于套管针切口处局部浸润20 mL 0.25%左旋布比卡因。第2组在拔管前30分钟静脉给予患者1g对乙酰氨基酚,并在术后24小时内静脉给予5g对乙酰氨基酚。第3组在拔管前30分钟静脉给予8mg氯诺昔康,并在术后24小时内静脉给予8mg氯诺昔康。在术后期间,评估疼痛评分、曲马多累积用量和额外哌替啶用量。
每组术后疼痛评分均显著降低(p < 0.05)。尽管术后1、2、4、8、12和24小时各组疼痛程度无显著差异,但第1组曲马多累积用量高于其他组。(第1组 = 370.6 ± 121.6 mg,第2组:220.9 ± 92.5mg,第3组 = 240.7 ± 100.4 mg。)(p < 0.005)。与第1组相比,第2组和第3组给予的哌替啶平均剂量显著更低(第1组:145 mg,第2组:100mg,第3组:100mg)(p = 0.024)。
在接受经腹腹腔镜肾脏和肾上腺手术的患者中,与对乙酰氨基酚组和氯诺昔康组相比,左旋布比卡因治疗组需要显著更多的静脉注射曲马多。