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用于后半规管良性阵发性位置性眩晕的Epley和Semont手法:一项网状荟萃分析。

Epley and Semont maneuvers for posterior canal benign paroxysmal positional vertigo: A network meta-analysis.

作者信息

Liu Yun, Wang Wei, Zhang Ao-Bo, Bai Xue, Zhang Shuang

机构信息

Otorhinolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, China.

出版信息

Laryngoscope. 2016 Apr;126(4):951-5. doi: 10.1002/lary.25688. Epub 2015 Sep 25.

Abstract

OBJECTIVES/HYPOTHESIS: Using network meta-analysis, we aimed to compare the efficacy and safety of Epley and Semont maneuvers as treatment options for posterior canal benign paroxysmal positional vertigo.

STUDY DESIGN

Network meta-analysis.

METHODS

Randomized controlled studies with a Jadad score ≥ 3 that used an Epley or Semont maneuver in posterior canal benign paroxysmal positional vertigo patients were analyzed in this project. The following efficacy outcomes included 1-week recovery rate and end of study recovery rate. Recurrence rate was used to assess the safety of each treatment.

RESULTS

Of 589 articles, 12 studies that enrolled 999 posterior canal benign paroxysmal positional vertigo patients were selected. The pooled analysis revealed that the Epley maneuver was as efficacious as the Semont maneuver, in both the 1-week recovery rate and end of study recovery rate (odds ratio [OR] = 1.8, 95% confidence interval [CI] = 0.48-7.00; OR = 1.8, 95% CI = 0.47-7.20), and had a similar recurrence rate (OR = 1.00, 95% CI = 0.33-4.4). These two techniques were both better than sham-controlled treatment in the two efficacy indicators. No difference was observed in recurrence rate for treatments.

CONCLUSIONS

The Epley maneuver was similar to the Semont maneuver in both efficacy and safety for posterior canal benign paroxysmal positional vertigo in short-term effects, and both were superior to the sham-controlled treatment.

LEVEL OF EVIDENCE

NA.

摘要

目的/假设:我们旨在通过网络荟萃分析比较Epley手法和Semont手法作为后半规管良性阵发性位置性眩晕治疗方案的疗效和安全性。

研究设计

网络荟萃分析。

方法

本项目分析了对后半规管良性阵发性位置性眩晕患者使用Epley或Semont手法且Jadad评分≥3的随机对照研究。以下疗效指标包括1周恢复率和研究结束时的恢复率。复发率用于评估每种治疗方法的安全性。

结果

在589篇文章中,选择了12项纳入999例后半规管良性阵发性位置性眩晕患者的研究。汇总分析显示,Epley手法在1周恢复率和研究结束时的恢复率方面与Semont手法疗效相当(优势比[OR]=1.8,95%置信区间[CI]=0.48 - 7.00;OR = 1.8,95% CI = 0.47 - 7.20),且复发率相似(OR = 1.00,95% CI = 0.33 - 4.4)。在这两个疗效指标上,这两种技术均优于假对照治疗。各治疗方法的复发率未观察到差异。

结论

Epley手法和Semont手法在治疗后半规管良性阵发性位置性眩晕的短期疗效和安全性方面相似,且均优于假对照治疗。

证据级别

无。

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