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因牙痛导致的对乙酰氨基酚过量:病例系列

Paracetamol overdose secondary to dental pain: a case series.

作者信息

Siddique I, Mahmood H, Mohammed-Ali R

机构信息

Sheffield Teaching Hospitals NHS Trust, Oral and Maxillofacial Surgery, Charles Clifford Dental Hospital, 76 Wellesley Road, Sheffield, S10 2SZ.

Oral and Maxillofacial Surgery, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF.

出版信息

Br Dent J. 2015 Sep 25;219(6):E6. doi: 10.1038/sj.bdj.2015.706.

Abstract

INTRODUCTION

There have been documented cases of serious and life-threatening health effects due to patients taking unintentional analgesia overdose secondary to dental pain. We aimed to determine firstly what proportion of unintentional paracetamol overdose cases admitted to an acute medical assessment unit (MAU) were secondary to dental pain, secondly what proportion of such cases encountered barriers to accessing emergency dental care and finally what clinical burden such cases placed on the hospital services.

METHOD

The clinical coding department provided information to allow appropriate identification and data collection from patient discharge summaries and case notes of all unintentional paracetamol overdose cases secondary to dental pain over a 24 month period (1 March 2012 to 28 February 2014).

RESULTS

One hundred and sixteen admissions were identified specifically for unintentional paracetamol overdose. Dental pain accounted for 48 (41%) of all cases. Females (67%) were twice as likely to be admitted, compared to males (33%), with a mean age of 36 years and four months. Thirty-two (63%) non-dentally registered and all nine (100%) registered patients were unable to access timely emergency dental care before their admission. Forty cases (83%) were referred to the hospital oral and maxillofacial services (OMFS). Thirty-seven (93%) patients underwent elective outpatient dental extractions and the remaining three (7%) patients were admitted for intravenous antibiotics, incision and drainage and dental extractions. All patients were treated under local anaesthetic.

CONCLUSION

Dental pain is the single most common cause of acute medical admission secondary to unintentional paracetamol overdose. Patients registered with a general dental practitioner (GDP), as well as those not registered with a GDP, had difficulty accessing timely emergency primary dental care.

摘要

引言

已有记录表明,患者因牙疼痛意外过量服用镇痛药会产生严重及危及生命的健康影响。我们旨在首先确定入住急性医疗评估单元(MAU)的意外对乙酰氨基酚过量病例中,因牙疼痛导致的病例占比,其次确定此类病例中,在获得紧急牙科护理方面遇到障碍的病例占比,最后确定此类病例给医院服务带来的临床负担。

方法

临床编码部门提供信息,以便从24个月期间(2012年3月1日至2014年2月28日)所有因牙疼痛导致意外对乙酰氨基酚过量病例的患者出院小结和病历中进行适当识别和数据收集。

结果

共确定了116例因意外对乙酰氨基酚过量而入院的病例。牙疼痛占所有病例的48例(41%)。女性(67%)入院的可能性是男性(33%)的两倍,平均年龄为36岁零4个月。32例(63%)未在牙科登记的患者以及所有9例(100%)登记患者在入院前均无法及时获得紧急牙科护理。40例(83%)患者被转诊至医院口腔颌面外科服务(OMFS)。37例(93%)患者接受了择期门诊拔牙,其余3例(7%)患者因静脉注射抗生素、切开引流和拔牙而入院。所有患者均在局部麻醉下接受治疗。

结论

牙疼痛是意外对乙酰氨基酚过量导致急性医疗入院的最常见单一原因。在普通牙科医生(GDP)处登记的患者以及未在GDP处登记的患者在及时获得紧急初级牙科护理方面均存在困难。

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