Larsen Sofie Krahl, Markvart Merete, Søndenbroe Rasmus, Dalhoff Kim, Jensen Simon Storgård
Department of Odontology, Section of Oral Biology and Immunopathology, University of Copenhagen, Copenhagen, Denmark.
Department of Odontology, Section of Clinical Oral Microbiology, University of Copenhagen, Copenhagen, Denmark.
Basic Clin Pharmacol Toxicol. 2025 Feb;136(2):e14124. doi: 10.1111/bcpt.14124.
Dental pain is common, and many patients use analgesics to alleviate the pain. Analgesics are readily accessible, and overdosing may lead to severe complications. This study explores the extent of analgesic overdosing in patients with dental pain. Data were collected from two dental emergency clinics in Copenhagen, Denmark, via questionnaires and interviews with 180 patients. Results showed that 82.8% (n = 149) had taken at least one type of analgesic, and 9% (n = 15) had exceeded the recommended maximum dosage. Of all patients with dental pain, 75.6% (n = 136) used paracetamol, 54.4% (n = 98) ibuprofen, 10% (n = 18) opioids, and 11.1% (n = 20) other types of analgesics. Most frequently, the pain was of pulpal origin (n = 119; 66.1%). Of all analgesics used, most were obtained places where guidance should be available, for example, pharmacies, dental clinics or hospitals (n = 152; 54%). The patients were aware of the recommended maximum daily dosage for paracetamol and ibuprofen in 39% (n = 70) and 41% (n = 73) of the cases, respectively. In conclusion, most patients with dental pain use analgesics to alleviate their pain. A substantial proportion of these patients overdose themselves, potentially putting them at risk of severe systemic complications. This study highlights the need for better patient education and safer pain management strategies.
牙痛很常见,许多患者使用镇痛药来缓解疼痛。镇痛药很容易获得,过量服用可能会导致严重并发症。本研究探讨了牙痛患者镇痛药过量服用的程度。通过对丹麦哥本哈根两家牙科急诊诊所的180名患者进行问卷调查和访谈收集数据。结果显示,82.8%(n = 149)的患者至少服用过一种镇痛药,9%(n = 15)的患者超过了推荐的最大剂量。在所有牙痛患者中,75.6%(n = 136)使用对乙酰氨基酚,54.4%(n = 98)使用布洛芬,10%(n = 18)使用阿片类药物,11.1%(n = 20)使用其他类型的镇痛药。最常见的是牙髓源性疼痛(n = 119;66.1%)。在所有使用的镇痛药中,大多数是在应该有指导的地方获得的,例如药店、牙科诊所或医院(n = 152;54%)。分别有39%(n = 70)和41%(n = 73)的患者知道对乙酰氨基酚和布洛芬的推荐最大日剂量。总之,大多数牙痛患者使用镇痛药来缓解疼痛。这些患者中有很大一部分过量服药,这可能使他们面临严重全身并发症的风险。本研究强调了加强患者教育和采用更安全的疼痛管理策略的必要性。