先天性弓形虫感染所致脑积水模式与寄生虫遗传学相关。
Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics.
作者信息
Hutson Samuel L, Wheeler Kelsey M, McLone David, Frim David, Penn Richard, Swisher Charles N, Heydemann Peter T, Boyer Kenneth M, Noble A Gwendolyn, Rabiah Peter, Withers Shawn, Montoya Jose G, Wroblewski Kristen, Karrison Theodore, Grigg Michael E, McLeod Rima
机构信息
Department of Ophthalmology and Visual Science, The University of Chicago.
Northwestern University and Lurie Children's Hospital and Medical Center.
出版信息
Clin Infect Dis. 2015 Dec 15;61(12):1831-4. doi: 10.1093/cid/civ720. Epub 2015 Sep 24.
Abstract
Four anatomical patterns of hydrocephalus secondary to congenital Toxoplasma gondii infection were identified and characterized for infants enrolled in the National Collaborative Chicago-based Congenital Toxoplasmosis Study. Analysis of parasite serotype revealed that different anatomical patterns associate with Type-II vs Not-Exclusively Type-II strains (NE-II) (P = .035).
摘要
针对参与基于芝加哥的全国先天性弓形虫病合作研究的婴儿，确定并描述了先天性弓形虫感染继发脑积水的四种解剖学模式。对寄生虫血清型的分析显示，不同的解剖学模式与II型菌株和非纯II型菌株（NE-II）相关（P = 0.035）。
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