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本文引用的文献

1
Severe South American ocular toxoplasmosis is associated with decreased Ifn-γ/Il-17a and increased Il-6/Il-13 intraocular levels.严重的南美眼弓形体病与眼内 IFN-γ/IL-17a 减少和 IL-6/IL-13 增加有关。
PLoS Negl Trop Dis. 2013 Nov 21;7(11):e2541. doi: 10.1371/journal.pntd.0002541. eCollection 2013 Nov.
2
Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981-2009).早产和严重程度与弓形体虫等位基因有关（NCCCTS，1981-2009）。
Clin Infect Dis. 2012 Jun;54(11):1595-605. doi: 10.1093/cid/cis258. Epub 2012 Apr 11.
3
Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells.三种经典弓形虫株对人神经上皮细胞基因表达的差异影响。
Infect Immun. 2011 Mar;79(3):1363-73. doi: 10.1128/IAI.00947-10. Epub 2010 Dec 13.
4
Globalization and the population structure of Toxoplasma gondii.弓形虫的全球化与种群结构
Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11423-8. doi: 10.1073/pnas.0601438103. Epub 2006 Jul 18.
5
Outcome of treatment for congenital toxoplasmosis, 1981-2004: the National Collaborative Chicago-Based, Congenital Toxoplasmosis Study.1981 - 2004年先天性弓形虫病的治疗结果：基于芝加哥的全国先天性弓形虫病协作研究
Clin Infect Dis. 2006 May 15;42(10):1383-94. doi: 10.1086/501360. Epub 2006 Apr 11.
6
Risk factors for Toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: Implications for prenatal management and screening.先天性弓形虫病患儿母亲感染弓形虫的危险因素：对产前管理和筛查的启示
Am J Obstet Gynecol. 2005 Feb;192(2):564-71. doi: 10.1016/j.ajog.2004.07.031.
7
Endoscopic third ventriculostomy in infants of less than 1 year of age: which factors influence the outcome?1岁以下婴儿的内镜下第三脑室造瘘术：哪些因素影响手术结果？
Childs Nerv Syst. 2004 Jun;20(6):405-11. doi: 10.1007/s00381-004-0958-7. Epub 2004 Apr 28.
8
Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease?刚地弓形虫的种群生物学及其与人类感染的相关性：不同菌株会导致不同疾病吗？
Curr Opin Microbiol. 2002 Aug;5(4):438-42. doi: 10.1016/s1369-5274(02)00349-1.
9
The impact of endoscopic third ventriculostomy on the management of newly diagnosed hydrocephalus in infants.内镜下第三脑室造瘘术对婴儿新诊断脑积水治疗的影响。
Pediatr Neurosurg. 2001 Sep;35(3):131-5. doi: 10.1159/000050406.
10
Congenital toxoplasmosis. The Toxoplasmosis Study Group.先天性弓形虫病。弓形虫病研究小组。
Semin Pediatr Neurol. 1994 Sep;1(1):4-25.

先天性弓形虫感染所致脑积水模式与寄生虫遗传学相关。

Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics.

作者信息

Hutson Samuel L, Wheeler Kelsey M, McLone David, Frim David, Penn Richard, Swisher Charles N, Heydemann Peter T, Boyer Kenneth M, Noble A Gwendolyn, Rabiah Peter, Withers Shawn, Montoya Jose G, Wroblewski Kristen, Karrison Theodore, Grigg Michael E, McLeod Rima

机构信息

Department of Ophthalmology and Visual Science, The University of Chicago.

Northwestern University and Lurie Children's Hospital and Medical Center.

出版信息

Clin Infect Dis. 2015 Dec 15;61(12):1831-4. doi: 10.1093/cid/civ720. Epub 2015 Sep 24.

DOI:10.1093/cid/civ720
PMID:26405147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4657535/
Abstract

Four anatomical patterns of hydrocephalus secondary to congenital Toxoplasma gondii infection were identified and characterized for infants enrolled in the National Collaborative Chicago-based Congenital Toxoplasmosis Study. Analysis of parasite serotype revealed that different anatomical patterns associate with Type-II vs Not-Exclusively Type-II strains (NE-II) (P = .035).

摘要

针对参与基于芝加哥的全国先天性弓形虫病合作研究的婴儿，确定并描述了先天性弓形虫感染继发脑积水的四种解剖学模式。对寄生虫血清型的分析显示，不同的解剖学模式与II型菌株和非纯II型菌株（NE-II）相关（P = 0.035）。