Moltz L, Becker K
Eur J Obstet Gynecol Reprod Biol. 1977;7(5):331-6. doi: 10.1016/0028-2243(77)90018-1.
The occurrence of cribriform adenomatous hyperplasia of the endocervical glands of the uterus was examined in 92 women, in whom punch biopsies of the ecto-endocervical line were taken during the second half of their cycle. Of these, 79 women had taken combined estrogen-progestogen preparations, 9 women had taken progestogens alone, while 14 patients formed a control group. There was a significant difference only between the control group without hormones and the groups treated with hormones. The groups of patients under the various regimens of hormonal treatment displayed a varying percentage of cribriform adenomatous hyperplasia. There was a clear tendency for such lesions to be observed more frequently under the combined type of contraception than under the sequential type. These differences were not, however, significant. A correlation with specific exogenous groups of steroids could not be established.
对92名女性子宫颈内膜腺筛状腺瘤样增生的发生情况进行了检查,这些女性在月经周期后半期接受了宫颈内外口连线处的活检。其中,79名女性服用了雌激素 - 孕激素联合制剂,9名女性仅服用了孕激素,而14名患者组成了对照组。仅在未使用激素的对照组与接受激素治疗的组之间存在显著差异。接受不同激素治疗方案的患者组中,筛状腺瘤样增生的比例各不相同。与序贯式避孕相比,联合式避孕下更常观察到此类病变,这一趋势较为明显。然而,这些差异并不显著。无法确定与特定外源性类固醇组之间的相关性。