在光学相干断层扫描中使用可编程相位调制器增强横向分辨率。

Lateral resolution enhancement using programmable phase modulator in optical coherence tomography.

作者信息

Shirazi Muhammad Faizan, Cho Nam Hyun, Jung Woonggyu, Kim Jeehyun

机构信息

School of Electronics Engineering, Kyungpook National University, Daegu,702-701, Korea.

School of Nano-Bioscience & Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea.

出版信息

Biomed Mater Eng. 2015;26 Suppl 1:S1465-71. doi: 10.3233/BME-151445.

DOI:10.3233/BME-151445

PMID:26405909

Abstract

Adaptive optics plays an important role in the correction of high-order aberrations to enhance lateral resolution. An OCT system coupled with a programmable phase modulator is designed to verify lateral resolution improvement. The Hamamatsu high-resolution, non-pixelized, optically addressed light modulator (PAL-SLM) PPM X7550 series is used to correct aberrations, utilizing a simple method based on phase information from OCT images. The advantages of this method are its high simplicity and low cost. A raster scanning technique is adopted to scan samples covered with scattering suspension. Metal lines covered with scattering suspension are imaged, and a respective correction is applied to remove the aberration. Results demonstrate an improvement in lateral resolution on metal grid samples.

摘要

自适应光学在高阶像差校正以提高横向分辨率方面发挥着重要作用。设计了一种结合可编程相位调制器的光学相干断层扫描（OCT）系统，以验证横向分辨率的提高。采用滨松高分辨率、非像素化、光寻址光调制器（PAL-SLM）PPM X7550系列，利用基于OCT图像相位信息的简单方法来校正像差。该方法的优点是高度简单且成本低。采用光栅扫描技术对覆盖有散射悬浮液的样品进行扫描。对覆盖有散射悬浮液的金属线进行成像，并应用相应的校正来消除像差。结果表明金属网格样品的横向分辨率有所提高。