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光学相干断层扫描中深度编码合成孔径的焦点扩展

Focus-extension by depth-encoded synthetic aperture in Optical Coherence Tomography.

作者信息

Mo Jianhua, de Groot Mattijs, de Boer Johannes F

机构信息

Institute for Lasers, Life and Biophotonics Amsterdam, Department of Physics and Astronomy, VU University Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands.

出版信息

Opt Express. 2013 Apr 22;21(8):10048-61. doi: 10.1364/OE.21.010048.

Abstract

We present a novel method to extend the depth-of-focus of Optical Coherence Tomography (OCT). OCT is an interferometric imaging technique that provides depth-resolved scattering information. The axial resolution in OCT is provided by the coherence gate and is invariant over the full image depth. The lateral resolution is determined by the beam parameters such as wavelength and numerical aperture. The Rayleigh range determines the depth range over which the lateral resolution can be maintained. The lateral resolution is often sacrificed to maintain relatively long Rayleigh range. In this study, we propose to use a depth-encoded synthetic aperture detection scheme to extend the depth range over which a sharp focus can be maintained beyond the Rayleigh range. An annular phase plate is inserted into the light path in the sample arm, which gives rise to three separate images in a single B-scan, corresponding to three different optical path length encoded apertures. These three images are coherently summed after phase-manipulation to reconstruct a new image with a lateral resolution that is maintained over a five times larger depth range.

摘要

我们提出了一种扩展光学相干断层扫描(OCT)焦深的新方法。OCT是一种干涉成像技术,可提供深度分辨的散射信息。OCT中的轴向分辨率由相干门提供,并且在整个图像深度上保持不变。横向分辨率由诸如波长和数值孔径等光束参数决定。瑞利范围决定了可以保持横向分辨率的深度范围。为了保持相对较长的瑞利范围,横向分辨率常常会被牺牲。在本研究中,我们建议使用深度编码合成孔径检测方案来扩展深度范围,在该深度范围内可以在瑞利范围之外保持清晰聚焦。在样品臂的光路中插入一个环形相位板,这会在单次B扫描中产生三个单独的图像,分别对应于三个不同的光程长度编码孔径。在进行相位处理后,将这三个图像相干相加,以重建一个新图像,其横向分辨率在五倍大的深度范围内得以保持。

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