聚乳酸/苯乙烯-乙烯-丁烯-苯乙烯复合材料的生物相容性及表征
Biocompatibility and characterization of polylactic acid/styrene-ethylene-butylene-styrene composites.
作者信息
Tsou Chi-Hui, Kao Bo-Jyue, Yang Ming-Chien, Suen Maw-Cherng, Lee Yi-Hsuan, Chen Jui-Chin, Yao Wei-Hua, Lin Shang-Ming, Tsou Chih-Yuan, Huang Shu-Hsien, De Guzman Manuel, Hung Wei-Song
机构信息
Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
R&D Center for Membrane Technology, Department of Chemical Engineering, Chung Yuan University, Jhongli 32023, Taiwan.
出版信息
Biomed Mater Eng. 2015;26 Suppl 1:S147-54. doi: 10.3233/BME-151300.
Polylactic acid (PLA)/styrene-ethylene-butylene-styrene (SEBS) composites were prepared by melt blending. Differential scanning calorimetry (DSC) and wide angle X-ray diffraction (WXRD) were used to characterize PLA and PLA/SEBS composites in terms of their melting behavior and crystallization. Curves from thermal gravimetric analysis (TGA) illustrated that thermostability increased with SEBS content. Further morphological analysis of PLA/SEBS composites revealed that SEBS molecules were not miscible with PLA molecules in PLA/SEBS composites. The tensile testing for PLA and PLA/SEBS composites showed that the elongation at the break was enhanced, but tensile strength decreased with increasing SEBS content. L929 fibroblast cells were chosen to assess the cytocompatibility; the cell growth of PLA was found to decrease with increasing SEBS content. This study proposes possible reasons for these properties of PLA/SEBS composites.
通过熔融共混制备了聚乳酸（PLA）/苯乙烯-乙烯-丁烯-苯乙烯（SEBS）复合材料。采用差示扫描量热法（DSC）和广角X射线衍射（WXRD）对PLA和PLA/SEBS复合材料的熔融行为和结晶情况进行了表征。热重分析（TGA）曲线表明，热稳定性随SEBS含量的增加而提高。对PLA/SEBS复合材料的进一步形态分析表明，在PLA/SEBS复合材料中，SEBS分子与PLA分子不相容。对PLA和PLA/SEBS复合材料的拉伸测试表明，随着SEBS含量的增加，断裂伸长率提高，但拉伸强度降低。选择L929成纤维细胞来评估细胞相容性；发现随着SEBS含量的增加，PLA的细胞生长减少。本研究提出了PLA/SEBS复合材料这些性能的可能原因。
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