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婴儿脑室内成星形细胞瘤:一例报告并文献复习

Intraventricular Astroblastoma in an Infant: A Case Report and Review of the Literature.

作者信息

Sabharwal Paramveer, Sadashiva Nishanth, Unchagi Asha, Mahadevan Anita, Pandey Paritosh

出版信息

Pediatr Neurosurg. 2015;50(6):325-9. doi: 10.1159/000369032. Epub 2015 Sep 26.

DOI:10.1159/000369032
PMID:26406441
Abstract

Astroblastomas are rare intracranial tumours of uncertain origin and are commonly present in the supratentorial compartment. Astroblastomas often affect children and young adults. Their occurrence in an intraventricular location, in an infant, is extremely uncommon. We describe a 1-year-old boy who presented with features of raised intracranial pressure. An MRI scan revealed an intralateral ventricular tumour. Complete excision was performed. Its histopathological examination revealed features consistent with astroblastoma. A follow-up MRI scan after 9 months did not show any residual tumour, and the patient was followed up without any adjuvant therapy. The radiological and histopathological characteristics of this tumour are described in our report.

摘要

成星形细胞瘤是起源不明的罕见颅内肿瘤,常见于幕上腔。成星形细胞瘤常影响儿童和年轻人。在婴儿的脑室内发生这种肿瘤极为罕见。我们描述了一名1岁男孩,他表现出颅内压升高的症状。磁共振成像(MRI)扫描显示侧脑室内有肿瘤。进行了完整切除。其组织病理学检查显示的特征符合成星形细胞瘤。9个月后的随访MRI扫描未显示任何残留肿瘤,且未进行任何辅助治疗对该患者进行了随访。我们的报告中描述了该肿瘤的影像学和组织病理学特征。

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引用本文的文献

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Cerebral astroblastoma radiologically mimicking pilocytic astrocytoma: A case report.影像学表现类似毛细胞型星形细胞瘤的大脑成星形细胞瘤:一例报告
Clin Case Rep. 2022 Apr 25;10(4):e05781. doi: 10.1002/ccr3.5781. eCollection 2022 Apr.
2
Patterns of care and survival outcomes in patients with astroblastoma: an individual patient data analysis of 152 cases.成星形细胞瘤患者的治疗模式与生存结局:152例患者的个体患者数据分析
Childs Nerv Syst. 2017 Aug;33(8):1295-1302. doi: 10.1007/s00381-017-3410-5. Epub 2017 May 5.
3
Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults.
成星形细胞瘤的形态学和分子特征,包括BRAFV600E突变,提示其与儿童和年轻成人的其他基于皮质的胶质瘤存在本体论关系。
Neuro Oncol. 2017 Jan;19(1):31-42. doi: 10.1093/neuonc/now118. Epub 2016 Jul 14.