Aarnoudse J G, Hovinga G, Huisjes H J
Eur J Obstet Gynecol Reprod Biol. 1978 Apr;8(2):105-8. doi: 10.1016/0028-2243(78)90137-5.
Successful fetal blood sampling by fetoscopy is reported in 4 out of 6 pregnant ewes. No deleterious effect of the procedure on the course of pregnancy and fetal outcome could be demonstrated. There were two main problems: floating membranes and mobile fetal cotyledon vessels. Although the first problem could in part be overcome by infusion of saline, fetal blood sampling in the pregnant ewe is a rather difficult and time-consuming procedure.
据报道,6只怀孕母羊中有4只通过胎儿镜检查成功采集到胎儿血液。未发现该操作对妊娠过程和胎儿结局有不良影响。存在两个主要问题:胎膜漂浮和胎儿绒毛叶血管移动。尽管通过注入生理盐水可以部分克服第一个问题,但在怀孕母羊中采集胎儿血液是一个相当困难且耗时的过程。