Calderón Tirza A, Coffin Susan E, Sammons Julia S
Perelman School of Medicine at the University of Pennsylvania, Philadelphia;
Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Department of Pediatrics and Division of Infectious Diseases, Department of Infection Prevention and Control, The Children's Hospital of Philadelphia, Pennsylvania.
J Pediatric Infect Dis Soc. 2015 Sep;4(3):252-9. doi: 10.1093/jpids/piu056. Epub 2014 Jun 17.
The surge in pertussis incidence in recent years underscores a critical need for effective plans to prevent transmission in pediatric healthcare settings. Adolescents and adults are common sources of infection for unimmunized or incompletely immunized infants and children with waning immunity. Despite documented outbreaks being limited in size, pertussis poses a threat to pediatric healthcare facilities due to the risk for widespread transmission, potentially severe complications among vulnerable patient populations, and high outbreak control-related costs. Healthcare personnel, visitors, and parents have been identified as sources of outbreaks, underscoring the importance of coordinated efforts to prevent transmission in these settings. This comprehensive review demonstrates that the risk of pertussis transmission in pediatric healthcare settings warrants heightened focus on strategies to recognize disease earlier, improve diagnostic evaluation, and facilitate effective contact tracing and post-exposure prophylaxis measures. This review suggests that healthcare personnel can play a significant role in the prevention of healthcare-associated pertussis.
近年来百日咳发病率的激增凸显了制定有效计划以防止其在儿科医疗环境中传播的迫切需求。青少年和成年人是未免疫或免疫不完全且免疫力逐渐减弱的婴幼儿常见的感染源。尽管有记录的疫情规模有限,但由于存在广泛传播的风险、弱势患者群体可能出现的严重并发症以及与疫情控制相关的高昂成本,百日咳对儿科医疗机构构成了威胁。医护人员、访客和家长已被确定为疫情的源头,这凸显了在这些环境中协同努力预防传播的重要性。这项全面综述表明,百日咳在儿科医疗环境中的传播风险值得高度关注识别疾病的策略,以更早地发现疾病、改善诊断评估,并促进有效的接触者追踪和暴露后预防措施。该综述表明,医护人员在预防医疗相关百日咳方面可发挥重要作用。