Fakhri Akbar, Shah Manish N, Goyal Manu S
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA.
Department of Pediatric Surgery, University of Texas, Health Science Center at Houston, 6431 Fannin Street, MSB 5.144, Houston, TX 77030, USA; Department of Neurosurgery, University of Texas, Health Science Center at Houston, 6431 Fannin Street, MSB 5.144, Houston, TX 77030, USA.
Neurosurg Clin N Am. 2015 Oct;26(4):519-26. doi: 10.1016/j.nec.2015.06.012.
Type I Chiari malformations are congenital deformities involving cerebellar tonsillar herniation downward through the foramen magnum. Structurally, greater than 5 mm of tonsillar descent in adults and more than 6 mm in children is consistent with type I Chiari malformations. However, the radiographic severity of the tonsillar descent does not always correlate well with the clinical symptomatology. Advanced imaging can help clinically correlate imaging to symptoms. Specifically, cerebrospinal fluid (CSF) flow abnormalities are seen in patients with type I Chiari malformation. Advanced MRI involving cardiac-gated and phase-contrast MRI affords a view of such CSF flow abnormalities.
I型Chiari畸形是一种先天性畸形，涉及小脑扁桃体通过枕骨大孔向下疝出。在结构上，成人扁桃体下移超过5毫米，儿童超过6毫米符合I型Chiari畸形。然而，扁桃体下移的影像学严重程度并不总是与临床症状密切相关。先进的影像学检查有助于在临床上将影像学表现与症状相关联。具体而言，I型Chiari畸形患者可见脑脊液（CSF）流动异常。涉及心脏门控和相位对比MRI的先进MRI可观察到此类CSF流动异常。
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