Dong Renwei, Wang Xiuyang, Guo Qi, Wang Jiazhong, Zhang Wen, Shen Suxing, Han Peipei, Ma Yixuan, Kang Li, Wang Menglu, Fu Liyuan, Jia Liye, Wang Liancheng, Niu Kaijun
Department of Rehabilitation Medicine, Cardiovascular Clinical College of Tianjin Medical University, TEDA International Cardiovascular Hospital, Tianjin, China. Department of Rehabilitation and Sports Medicine, Tianjin Medical University, Tianjin, China.
Department of Rehabilitation and Sports Medicine, Tianjin Medical University, Tianjin, China.
J Gerontol A Biol Sci Med Sci. 2016 Jan;71(1):96-102. doi: 10.1093/gerona/glv168. Epub 2015 Sep 25.
More efficient clinical indexes are needed to identify older people most likely to present mobility impairments. The aim of the present study was to determine which handgrip strength (HS) indexes are clinically relevant to detect risk of mobility limitation in the elderly adults. In addition, we attempted to determine an optimal cutoff point for the most relevant index.
Data are from 469 men and 609 women aged 60 years and older recruited in the Hangu area of Tianjin, China. Participants scoring in the top 20% on the Timed Up and Go Test or in the slowest 20% for the 4-m walk test were defined as having mobility limitation.
The prevalence of mobility limitation was 27.6% in women and 24.5% in men. The area under the receiver-operating characteristic curve for HS/body fat mass was 0.723 (95% confidence interval [CI] = 0.658-0.788) in men and for HS/weight was 0.684 (95% CI = 0.628-0.739) in women. These values were indicated higher levels of mobility limitation compared with HS and other relative HS indexes. The cutoffs of the most relevant index in men and women that effectively identified individuals at risk of mobility limitation were 1.884 and 0.281, respectively.
HS/body fat mass and HS/weight appear to be the indices best associated with mobility limitation for men and women, respectively. Optimal cutoffs for clinically relevant index have the potential to identify elderly adults at risk of mobility limitation.
需要更有效的临床指标来识别最有可能出现行动障碍的老年人。本研究的目的是确定哪些握力(HS)指标在临床上与检测老年人行动受限风险相关。此外,我们试图确定最相关指标的最佳截断点。
数据来自中国天津汉沽地区招募的469名60岁及以上男性和609名60岁及以上女性。在定时起立行走测试中得分在前20%或4米步行测试中速度最慢的20%的参与者被定义为有行动受限。
女性行动受限患病率为27.6%,男性为24.5%。男性中HS/体脂量的受试者工作特征曲线下面积为0.723(95%置信区间[CI]=0.658 - 0.788),女性中HS/体重的受试者工作特征曲线下面积为0.684(95%CI = 0.628 - 0.739)。与HS和其他相对HS指标相比,这些值表明行动受限水平更高。男性和女性中最相关指标有效识别行动受限风险个体的截断点分别为1.884和0.281。
HS/体脂量和HS/体重似乎分别是与男性和女性行动受限最相关的指标。临床相关指标的最佳截断点有可能识别有行动受限风险的老年人。