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[白塞病的免疫抑制治疗。长期结果]

[Immunosuppressive treatment of Behçet's syndrome. Long-term results].

作者信息

Martenet A C, Paccolat F

出版信息

Ophtalmologie. 1989 Jan-Mar;3(1):40-2.

PMID:2641069
Abstract

We present middle and long-term results of cyclophosphamide and procarbazine therapy of Behçet's uveitis. Of 45 patients, 20 were followed for 1-4 years (14 successful cases, 5 satisfactory results with regression of inflammatory signs but no functional improvement, 1 failure), 17 for 5-10 years (9 successes, 5 satisfactory results, 3 failures), and 8 for 11-16 years (2 successes, 2 satisfactory results, 4 failures). The high percentage of success (over 55%) could be attributed partly to the early onset of therapy and may be partly to the choice of drugs.

摘要

我们展示了环磷酰胺和丙卡巴肼治疗白塞氏葡萄膜炎的中长期结果。45例患者中,20例随访了1至4年(14例成功,5例炎症体征消退但功能无改善的满意结果,1例失败),17例随访了5至10年(9例成功,5例满意结果,3例失败),8例随访了11至16年(2例成功,2例满意结果,4例失败)。高成功率(超过55%)部分可归因于治疗开始早,部分可能归因于药物选择。

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