Wright Tricia E
Department of Obstetrics, Gynecology and Women's Health University of Hawaii John A. Burns School of Medicine, 1319 Punahou St., Ste 824, Honolulu, HI 96826, USA.
Drug Metab Lett. 2015;9(2):65-71. doi: 10.2174/1872312809666150904182334.
Licit and illicit drug use is a common complication of pregnancy. Accurate information on drug use is difficult to obtain for many reasons as women fear self-disclosure or consenting for drug testing due to stigma, guilt, and fear of social and legal harm. As information about drug use is clinically very important, biochemical testing is an important adjunct to careful maternal history. In addition, research studies depend on accurate measures of exposure when reporting risks of a substance. This paper delineates available matrices for and methods of biochemical drug testing in pregnant women and neonates.
合法及非法药物使用是孕期常见的并发症。由于女性担心因污名、内疚以及对社会和法律伤害的恐惧而自我披露或同意进行药物检测，所以出于多种原因很难获得关于药物使用的准确信息。由于药物使用信息在临床上非常重要，生化检测是仔细询问母亲病史的重要辅助手段。此外，研究报告某种物质的风险时，依赖于对暴露情况的准确测量。本文阐述了孕妇和新生儿生化药物检测可用的样本基质及方法。
