Tangen Lena F, Lundbom Janne S, Skarsvåg Trine I, Wågø Kathrine J, Ballo Solveig, Hjelseng Tonje, Finsen Vilhjalmur
a Faculty of Medicine, NTNU , Trondheim , Norway.
b Department of Orthopaedic Surgery , St. Olav's University Hospital , Trondheim , Norway.
J Plast Surg Hand Surg. 2016;50(1):7-9. doi: 10.3109/2000656X.2015.1058269. Epub 2015 Sep 28.
To determine the influence of injection speed on pain during injection of local anaesthetics.
In a blinded randomised study with 36 healthy volunteers, each volunteer received three injections of 4.5 ml lidocaine subcutaneously on the abdomen. The injections were given during 15 seconds (0.3 ml/s), 30 seconds (0.15 ml/s), and 45 seconds (0.1 ml/s). The needle tip remained beneath the skin for 45 seconds during all three injections. Participants rated the pain experienced on a 100 mm visual analogue scale (VAS) immediately after each injection. After the last injection, they were asked which injections were the least and most painful.
The mean VAS pain score for the 15 seconds injections was 26 (SD = 19), for the 30 seconds injections 24 (SD = 19), and for the 45 seconds injections also 24 (SD = 18) (ns). Eight subjects preferred the 15 seconds injection, 15 preferred the 30 seconds injection, and 10 preferred the 45 seconds injection (ns).
It is concluded that varying the injection speed between 0.3 ml/s and 0.1 ml/s has no influence on the pain experienced during subcutaneous injection of 4.5 ml lidocaine.
确定注射速度对局部麻醉药注射时疼痛的影响。
在一项针对36名健康志愿者的双盲随机研究中，每位志愿者在腹部皮下接受三次4.5毫升利多卡因注射。注射分别在15秒（0.3毫升/秒）、30秒（0.15毫升/秒）和45秒（0.1毫升/秒）内完成。在所有三次注射过程中，针尖都留在皮肤下方45秒。每次注射后，参与者立即在100毫米视觉模拟量表（VAS）上对所经历的疼痛进行评分。在最后一次注射后，询问他们哪次注射最不痛和最痛。
15秒注射的平均VAS疼痛评分为26（标准差 = 19），30秒注射为24（标准差 = 19），45秒注射也为24（标准差 = 18）（无显著差异）。8名受试者更喜欢15秒的注射，15名更喜欢30秒的注射，10名更喜欢45秒的注射（无显著差异）。
得出结论，在0.3毫升/秒至0.1毫升/秒之间改变注射速度对皮下注射4.5毫升利多卡因时所经历的疼痛没有影响。
