Wang Michael L, Bailey Nathanael G
From the Department of Pathology, University of Michigan, Ann Arbor.
Arch Pathol Lab Med. 2015 Oct;139(10):1215-23. doi: 10.5858/arpa.2015-0203-RA.
Acute myeloid leukemia is a category of diseases with a common aggressive clinical presentation but with a prognosis and management that is dependent upon the underlying genetic characteristics of the neoplasm. The purpose of this brief review is to update the practicing pathologist on the current standard of care in the genetic evaluation of acute myeloid leukemia and to highlight future directions in the classification, genetic assessment, and management of these devastating diseases.
急性髓系白血病是一类具有共同侵袭性临床表现的疾病，但其预后和治疗取决于肿瘤的潜在遗传特征。本简要综述的目的是向执业病理学家介绍急性髓系白血病基因评估的当前护理标准，并强调这些毁灭性疾病在分类、基因评估和治疗方面的未来方向。
