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大脑对重复性感觉刺激反应的功能成像:从脑电图和单光子发射计算机断层扫描估计的来源

Functional imaging of brain responses to repetitive sensory stimulation: sources estimated from EEG and SPECT.

作者信息

Weinberg H, Johnson B, Cohen P, Crisp D, Robertson A

机构信息

Brain Behavior Laboratory, Simon Fraser University, Burnaby, B.C., Canada.

出版信息

Brain Topogr. 1989 Fall-Winter;2(1-2):171-80. doi: 10.1007/BF01128854.

DOI:10.1007/BF01128854
PMID:2641470
Abstract

This study examined the effect of modality of stimulation on two measures of cerebral function: (a) the scalp distribution of sensory evoked potentials and (b) the cerebral distribution of radiolabelled HMPAO. Steady-state stimulation in the auditory, somatosensory or visual modality was presented to six subjects. Scalp potentials were measured from a distribution of electrodes, and the radiopharmaceutical was injected through an indwelling intravenous catheter midway through the stimulation/recording session. Equivalent dipole sources estimated from the spatial distribution of the scalp potentials were found to be consistent with regions of high HMPAO uptake as imaged by Single Photon Emission Computed Tomography (SPECT).

摘要

本研究考察了刺激方式对脑功能两项指标的影响

(a)感觉诱发电位的头皮分布,以及(b)放射性标记的六甲基丙二胺肟(HMPAO)的脑内分布。对6名受试者进行听觉、体感或视觉方式的稳态刺激。从一组电极分布测量头皮电位,并在刺激/记录时段进行到一半时,通过留置静脉导管注射放射性药物。从头皮电位空间分布估计的等效偶极子源,被发现与单光子发射计算机断层扫描(SPECT)成像的高HMPAO摄取区域一致。

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Tactile and auditory stimuli repeated at high rates (30-50 per sec) produce similar event related potentials.以高频率(每秒30 - 50次)重复的触觉和听觉刺激会产生相似的事件相关电位。
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