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40赫兹听觉事件相关电位:正常值及病变的影响。

The 40 Hertz auditory event-related potential: normal values and effects of lesions.

作者信息

Spydell J D, Pattee G, Goldie W D

出版信息

Electroencephalogr Clin Neurophysiol. 1985 May;62(3):193-202. doi: 10.1016/0168-5597(85)90014-0.

DOI:10.1016/0168-5597(85)90014-0
PMID:2581759
Abstract

A model of the 40 Hz auditory event-related potential (40 Hz AERP) was developed and evaluated in a group of normal subjects and two patient groups. The model views the 40 Hz AERP as a combination of the brain-stem auditory evoked potential (BAEP) and a sinusoidal component presumed to arise from structures rostral to the brain-stem. Fourier analysis techniques were used to quantify changes in the sinusoidal component. The results obtained demonstrated that the phase of the sinusoidal component was quite stable in normal subjects, but was predictably altered as a consequence of thalamic or midbrain lesions. Lesions of the temporal lobe did not alter the phase of the sinusoidal component. These results were interpreted as being consistent with the model developed and suggesting a midbrain or thalamic origin for the 40 Hz sinusoid.

摘要

在一组正常受试者和两组患者中开发并评估了一种40赫兹听觉事件相关电位(40 Hz AERP)模型。该模型将40 Hz AERP视为脑干听觉诱发电位(BAEP)与假定源自脑干前方结构的正弦波成分的组合。使用傅里叶分析技术来量化正弦波成分的变化。获得的结果表明,正弦波成分的相位在正常受试者中相当稳定,但由于丘脑或中脑病变而可预测地发生改变。颞叶病变并未改变正弦波成分的相位。这些结果被解释为与所开发的模型一致,并表明40赫兹正弦波起源于中脑或丘脑。

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