Ocak Duran Ayse, Yildirim Afra, Inanc Mevlude, Karaca Halit, Berk Veli, Bozkurt Oktay, Ozaslan Ersin, Ucar Mahmut, Ozkan Metin
1Department of Medical Oncology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
J BUON. 2015 Jul-Aug;20(4):963-9.
To investigate the relationship between hepatic steatosis (HS) (at the time of diagnosis) and hepatic metastasis (at the time of diagnosis and follow-up) in metastatic breast cancer (BC) patients by using computed tomography (CT).
A total of 107 metastatic BC patients who had an abdominal CT were retrospectively enrolled in this study. Patients without HS (N=79) were regarded as the control group and those with HS constituted the HS study group (N-28).
Hepatic metastases at diagnosis and during follow-up were more common in patients with HS (p=0.018 and p=0.041, respectively) and in the premenopausal group (p<0.001 and p=0.004, respectively), whereas they were similar in patients with and without HS in the postmenopausal group (p=0.655 and p=0.656, respectively). Overall survival rates were similar in patients with and without HS (p=0.606).
Hepatic metastases at diagnosis and during follow-up were more frequent in patients with HS, especially in premenopausal patients. Survival was similar in both groups.
通过计算机断层扫描（CT）研究转移性乳腺癌（BC）患者诊断时的肝脂肪变性（HS）与诊断及随访时肝转移之间的关系。
本研究回顾性纳入了107例行腹部CT检查的转移性BC患者。无HS的患者（N = 79）被视为对照组，有HS的患者构成HS研究组（N = 28）。
诊断时及随访期间肝转移在有HS的患者中更常见（分别为p = 0.018和p = 0.041），在绝经前组中也更常见（分别为p < 0.001和p = 0.004），而在绝经后组中有HS和无HS的患者中肝转移情况相似（分别为p = 0.655和p = 0.656）。有HS和无HS的患者总生存率相似（p = 0.606）。
诊断时及随访期间肝转移在有HS的患者中更频繁，尤其是绝经前患者。两组生存率相似。
