Rengo S, Canonico V, Simeone M, Fortunato L, Tedeschi C
Arch Stomatol (Napoli). 1989 Oct;30(4):843-52.
Twenty-two cardiopathic patients (mean age 54.4 +/- 9.9 years) underwent dynamic electrocardiography during tooth extraction under local anesthesia (mepivacaine hydrochloride 2% plus adrenalin 1:200.000). Heart rate (p less than 0.001), systolic and diastolic blood pressure (p less than 0.001) significantly increased during tooth extraction returning to values near to basal level in the recovery period. No patients showed significant changes in ST segment. One patient with chronic atrial fibrillation presented an increase in ventricular rate (180 beats/min) and appearance of premature ventricular beats, spontaneously regressed. In conclusion, in cardiopathic patients dental operations by local anesthesia with vessel constriction it is possible, provided estimated clinical conditions of patients.
22名心脏病患者（平均年龄54.4±9.9岁）在局部麻醉（2%盐酸甲哌卡因加1:200000肾上腺素）下拔牙时接受了动态心电图检查。拔牙期间心率（p<0.001）、收缩压和舒张压（p<0.001）显著升高，恢复期恢复至接近基础水平的值。所有患者ST段均无显著变化。1例慢性心房颤动患者心室率增加（180次/分钟）并出现室性早搏，随后自行消退。总之，对于心脏病患者，在具备患者估计临床状况的前提下，采用局部麻醉加血管收缩剂进行牙科手术是可行的。
