al-Hathal M, Malmfors G, Garwicz S, Békássy A N
Department of Pediatrics, University Hospital, Lund, Sweden.
Pediatr Hematol Oncol. 1989;6(1):17-22. doi: 10.3109/08880018909014575.
Complications related to Port-A-Cath were studied prospectively during a period of 32 months in 31 patients, aged 1-18 years, with leukemias and solid tumors. There were 34 Port-A-Cath inserted, and the cumulative time for these catheters kept in place was 5899 days. No complications occurred in 18 patients (19 catheters) kept in place for a cumulative time of 3998 days with an average duration of 210 days (12-550 days). In 13 patients (15 catheters) there were 14 events of systemic infections; seven events were treated successfully with antibiotics, four events necessitated the extraction of the catheter (in one patient a combination of systemic and local infection), and in three events the catheters were kept unused, as the patients were in terminal stages. Nonsystemic complications occurred with five catheters; two local infections, two obstructions (catheters removed), and one local bleeding (catheter kept unused). Appropriate antimicrobial treatment of systemic infections enables the immunocompromised child to keep the Port-A-Cath in place for a long time.
在31例年龄1至18岁的白血病和实体瘤患者中，对与植入式静脉输液港相关的并发症进行了为期32个月的前瞻性研究。共植入34个植入式静脉输液港，这些导管的累计留置时间为5899天。18例患者（19个导管）累计留置3998天，平均留置时间为210天（12至550天），未发生并发症。13例患者（15个导管）发生了14次全身感染事件；7次事件通过抗生素治疗成功，4次事件需要拔除导管（1例患者同时发生全身和局部感染），3次事件中导管未使用，因为患者处于终末期。5个导管出现非全身并发症；2次局部感染、2次堵塞（导管拔除）和1次局部出血（导管未使用）。对全身感染进行适当的抗菌治疗可使免疫功能低下的儿童长时间保留植入式静脉输液港。
