皮质醇作为惊恐障碍患者下丘脑-垂体-肾上腺轴失调的指标：一项文献综述
Cortisol as an indicator of hypothalmic-pitituary-adrenal axis dysregulation in patients with panic disorder: a literature review.
作者信息
Jakuszkowiak-Wojten Katarzyna, Landowski Jerzy, Wiglusz Mariusz S, Cubała Wiesław Jerzy
机构信息
Department of Psychiatry, Medical University of Gdańsk, Dębinki 7 St. build. 25, 80-952 Gdańsk, Poland,
出版信息
Psychiatr Danub. 2015 Sep;27 Suppl 1:S445-51.
Dysregulation of hypothalamic-pituitary-adrenal axis (HPA) is seen in numerous mental disorders. Data of HPA axis disturbance in panic disorder are inconsistent. In panic disorder HPA axis hyperactivity has been observed with elevated cortisol levels. However, hypocortisolism has also been noted. Salivary cortisol as a biomarker of HPA-axis activity has received special attention. The aim of this paper is to review the findings on cortisol levels in panic disorder.
下丘脑-垂体-肾上腺轴（HPA）功能失调在众多精神障碍中都有体现。惊恐障碍中HPA轴紊乱的数据并不一致。在惊恐障碍中，已观察到HPA轴功能亢进，皮质醇水平升高。然而，也有低皮质醇血症的报道。唾液皮质醇作为HPA轴活动的生物标志物受到了特别关注。本文旨在综述惊恐障碍中皮质醇水平的研究结果。
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