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与感染途径相关的活动与类鼻疽临床症状之间的关联。

Association between activities related to routes of infection and clinical manifestations of melioidosis.

作者信息

Lim C, Peacock S J, Limmathurotsakul D

机构信息

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Clin Microbiol Infect. 2016 Jan;22(1):79.e1-79.e3. doi: 10.1016/j.cmi.2015.09.016. Epub 2015 Sep 28.

DOI:10.1016/j.cmi.2015.09.016
PMID:26417852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4721533/
Abstract

We sought associations between route of infection by Burkholderia pseudomallei and clinical manifestations in 330 cases of melioidosis in northeast Thailand using bivariate multivariable logistic regression models. Activities related to skin inoculation were negatively associated with bacteraemia, activities related to ingestion were associated with bacteraemia, and activities related to inhalation were associated with pneumonia. Our study suggests that route of infection is one of the factors related to clinical manifestations of melioidosis.

摘要

我们使用双变量多变量逻辑回归模型，在泰国东北部330例类鼻疽病患者中，探寻类鼻疽杆菌感染途径与临床表现之间的关联。与皮肤接种相关的活动与菌血症呈负相关，与摄入相关的活动与菌血症有关，与吸入相关的活动与肺炎有关。我们的研究表明，感染途径是与类鼻疽病临床表现相关的因素之一。

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本文引用的文献

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