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[转铁蛋白C与特应性皮炎之间的相关性研究]

[Examination of the correlation between transferrin C and atopic dermatitis].

作者信息

Cisło M, Leśko D, Blizanowska A

出版信息

Przegl Dermatol. 1989 Sep-Dec;76(5-6):386-90.

PMID:2641807
Abstract

Transferrin subtypes are considered to be some of genetic markers which can correlate with the incidence of certain diseases. The present study was designed to find out whether such a correlation is true for atopic dermatitis. Transferrin C subtypes (Tf CI, Tf C2, Tf C3) in blood serum were determined by the method of isoelectric focussing in polyacrylamide gel. Examinations were made in 30 atopic dermatitis patients. The control group was made up by a Polish population sample of 728 normal persons of both sexes. The results obtained were analysed statistically by means of test chi 2. There was no correlation between Tf C and atopic dermatitis (chi 2 = 0,638, d.f. = 2, 0,750 greater than p greater than 0,500).

摘要

转铁蛋白亚型被认为是一些可与某些疾病发病率相关的遗传标记。本研究旨在查明这种相关性对于特应性皮炎是否成立。采用聚丙烯酰胺凝胶等电聚焦法测定血清中转铁蛋白C亚型(Tf CI、Tf C2、Tf C3)。对30例特应性皮炎患者进行了检查。对照组由728名波兰男女正常人的样本组成。所得结果采用卡方检验进行统计学分析。转铁蛋白C与特应性皮炎之间无相关性(卡方 = 0.638,自由度 = 2,0.750>p>0.500)。

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