斑秃患者甲状腺的结构和功能异常

[Abnormalities of structure and function of the thyroid in patients with alopecia areata].

作者信息

Broniarczyk-Dyła G, Lewiński A, Zerek-Meleń G, Sewerynek E, Woźniacka A

出版信息

Przegl Dermatol. 1989 Sep-Dec;76(5-6):416-21.

Abstract

In 85 patients with alopecia areata the frequency of thyroid disease was assessed on the basis of history data, clinical examination and determination of T3, T4, TSH and presence of antithyroid antibodies of different specificity (ATMA, ATg, AMD). Among these patients abnormalities of thyroid structure and function were significantly more frequent (78%) than in the control group (33%). In 11% of the patients autoimmune thyroid disease was present (Graves-Basdow disease, Hashimoto thyroiditis). In 86 controls no cases of autoimmune diseases were found. In some patients only a slight enlargement of the thyroid was present (grade OB, I.).

摘要

在85例斑秃患者中，根据病史资料、临床检查以及T3、T4、促甲状腺激素（TSH）的测定和不同特异性抗甲状腺抗体（抗甲状腺微粒体抗体、抗甲状腺球蛋白抗体、抗甲状腺过氧化物酶抗体）的存在情况，对甲状腺疾病的发生率进行了评估。在这些患者中，甲状腺结构和功能异常的发生率（78%）显著高于对照组（33%）。11%的患者患有自身免疫性甲状腺疾病（格雷夫斯-巴塞多病、桥本甲状腺炎）。在86名对照者中未发现自身免疫性疾病病例。在一些患者中，仅存在甲状腺轻度肿大（OB级，I度）。