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[斑秃相关的内分泌紊乱——一项针对27例患者的研究]

[Endocrinological disorders in association with alopecia areata-a 27 patients study].

作者信息

Suditu G, Preda C, Vulpoi C, Toma A

机构信息

Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Centrul Medical Nicolina Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2001 Jul-Sep;105(3):533-5.

PMID:12092188
Abstract

Alopecia areata is a dermatological disease, characterized by the loss of hair, which affect men, women and children and can evaluate alone or in association with a variety of other disorders. Between these endocrinological diseases, especial thyroid disorders, have a high incidence. Twenty-seven patients with alopecia areata (12 women and 15 men) aged between 3 and 46 years were endocrinologically investigated. Eighteen of them (66.6%) had endocrinological disorders. Thyroid diseases were present in 10 cases (37%): 4 cases with endemic goiter, 2 cases with nodular goiter and 4 cases with hypothyroidism (1 case with autoimmune thyroiditis, 1 case with nodular goiter, 1 case with cystic goiter and 1 case with hypothyroidism post thyroidectomy for thyroidal lymphoma). Twelve cases (44.4%) were found with tetania. The incidence of thyroid diseases in alopecia areata is higher then in general population (2%), as well as the incidence of tetania. These evidences suggest that it is necessary to make a screening of endocrinological disorders in patients with alopecia areata.

摘要

斑秃是一种皮肤病,其特征为脱发,可影响男性、女性和儿童,可单独出现或与多种其他病症并发。在这些内分泌疾病中,尤其是甲状腺疾病,发病率较高。对27例年龄在3至46岁之间的斑秃患者(12名女性和15名男性)进行了内分泌学调查。其中18例(66.6%)患有内分泌疾病。甲状腺疾病有10例(37%):4例患有地方性甲状腺肿,2例患有结节性甲状腺肿,4例患有甲状腺功能减退(1例患有自身免疫性甲状腺炎,1例患有结节性甲状腺肿,1例患有囊性甲状腺肿,1例因甲状腺淋巴瘤行甲状腺切除术后出现甲状腺功能减退)。发现12例(44.4%)患有手足搐搦症。斑秃患者中甲状腺疾病的发病率高于普通人群(2%),手足搐搦症的发病率也是如此。这些证据表明,有必要对斑秃患者进行内分泌疾病筛查。

相似文献

1
[Endocrinological disorders in association with alopecia areata-a 27 patients study].[斑秃相关的内分泌紊乱——一项针对27例患者的研究]
Rev Med Chir Soc Med Nat Iasi. 2001 Jul-Sep;105(3):533-5.
2
[Abnormalities of structure and function of the thyroid in patients with alopecia areata].斑秃患者甲状腺的结构和功能异常
Przegl Dermatol. 1989 Sep-Dec;76(5-6):416-21.
3
A case series of alopecia areata in children: impact of personal and family history of stress and autoimmunity.儿童斑秃病例系列:压力和自身免疫的个人及家族史的影响
J Eur Acad Dermatol Venereol. 2007 Mar;21(3):356-9. doi: 10.1111/j.1468-3083.2006.01931.x.
4
[Value of pathologic thyroid gland findings in alopecia areata].[斑秃中甲状腺病理检查结果的价值]
Z Hautkr. 1987 Sep 1;62(17):1253-61.
5
[Alopecia areata and diseases of the thyroid gland].[斑秃与甲状腺疾病]
Dermatologica. 1971;142(1):62-3.
6
Thyroid autoimmunity in patients with alopecia areata.斑秃患者的甲状腺自身免疫
Acta Dermatovenerol Croat. 2008;16(3):123-5.
7
Increased risk for type I (insulin-dependent) diabetes in relatives of patients with alopecia areata (AA).斑秃(AA)患者亲属患I型(胰岛素依赖型)糖尿病的风险增加。
Am J Med Genet. 1994 Jul 1;51(3):234-9. doi: 10.1002/ajmg.1320510313.
8
Alopecia areata.斑秃
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Prevalence of thyroid diseases in patients with alopecia areata.
Int J Dermatol. 1994 Sep;33(9):632-3. doi: 10.1111/j.1365-4362.1994.tb02921.x.
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[Alopecia areata and thyroid diseases].斑秃与甲状腺疾病
Medicina (Firenze). 1988 Apr-Jun;8(2):185-7.