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膜性肾病与IgA肾病并存

Coexisting Membranous Nephropathy and IgA Nephropathy.

作者信息

Nishida Masashi, Kato Ryuichi, Hamaoka Kenji

机构信息

a Department of Pediatric Cardiology and Nephrology , Kyoto Prefectural University of Medicine, Graduate School of Medical Science , Kyoto , Japan.

出版信息

Fetal Pediatr Pathol. 2015;34(6):351-4. doi: 10.3109/15513815.2015.1087607. Epub 2015 Sep 29.

DOI:10.3109/15513815.2015.1087607
PMID:26418809
Abstract

We herein present a case of a 14-year-old boy with the histological features of coexisting membranous nephropathy (MN) and IgA nephropathy (IgAN). Asymptomatic hematuria/proteinuria was initially detected in school urinary screening, with treatments including oral corticosteroids leading to complete remission. Cases of coexisting MN and IgAN are very rare among the pediatric population; however, the overlap of these two nephropathies does not always imply a deleterious clinical outcome in pediatric cases.

摘要

我们在此报告一例14岁男孩,其具有膜性肾病(MN)和IgA肾病(IgAN)共存的组织学特征。无症状血尿/蛋白尿最初是在学校尿液筛查中发现的,治疗包括口服皮质类固醇,最终完全缓解。MN和IgAN共存的病例在儿科人群中非常罕见;然而,在儿科病例中,这两种肾病的重叠并不总是意味着有害的临床结果。

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Cureus. 2021 Sep 15;13(9):e18006. doi: 10.7759/cureus.18006. eCollection 2021 Sep.
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Associations between genetic risk variants for kidney diseases and kidney disease etiology.肾脏疾病遗传风险变异与肾脏疾病病因的关联。
Sci Rep. 2017 Oct 24;7(1):13944. doi: 10.1038/s41598-017-13356-6.
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Risk alleles for IgA nephropathy-associated SNPs conferred completely opposite effects to idiopathic membranous nephropathy in Chinese Han.
在中国汉族人群中,IgA 肾病相关 SNP 的风险等位基因与特发性膜性肾病的作用完全相反。
Immunol Res. 2017 Oct;65(5):1059-1064. doi: 10.1007/s12026-017-8947-6.
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Comparison of prognostic, clinical, and renal histopathological characteristics of overlapping idiopathic membranous nephropathy and IgA nephropathy versus idiopathic membranous nephropathy.比较重叠特发性膜性肾病和 IgA 肾病与特发性膜性肾病的预后、临床和肾组织病理特征。
Sci Rep. 2017 Sep 13;7(1):11468. doi: 10.1038/s41598-017-11838-1.