Samofalova D A, Karpov P A, Blume Ya B
Tsitol Genet. 2015 Jul-Aug;49(4):3-10.
The study presents the results of bioinformatic comparison of protein phosphatases from higher plants and human phosphatom (150 sequences). Based on sequence and profile comparison with known catalytic domains, 204 plant homologues from Physcomitrella patens and Arabidopsis thaliana where selected. Clustering of joint group of plant and mammalian protein phosphatases revealed fundamental differences in plant and human phosphatomes. At the same time, it was shown significant differences in the set of protein phosphatases in P. patens, A. thaliana, and such monocots as Orysa saliva and Zea mays.
该研究展示了高等植物和人类磷酸酶组（150个序列）的蛋白质磷酸酶的生物信息学比较结果。基于与已知催化结构域的序列和图谱比较，从地钱和拟南芥中选择了204个植物同源物。植物和哺乳动物蛋白质磷酸酶联合组的聚类揭示了植物和人类磷酸酶组的根本差异。同时，研究表明地钱、拟南芥以及单子叶植物水稻和玉米的蛋白质磷酸酶集合存在显著差异。
