Kruszyński Z, Podstawska D, Wojciechowska D, Wojtalik M
Pediatr Pol. 1989 Oct-Dec;64(10-12):612-8.
Effect of dopamine at the dose of 3 and 6 micrograms/kg/min on the systolic time intervals (STI) in 16 children after open heart surgery has been examined. The basic hemodynamic parameters --heart rate, systolic, diastolic and mean blood pressure have also been evaluated. Heart rate did not change during either rate of dopamine infusion. Systolic, diastolic and mean blood pressure increased significantly during the higher dose of dopamine. The dose of 3 and 6 micrograms/kg/min of dopamine decreased significantly the relation between pre-ejection period (PEP) and left-ventricular++ ejection time (LVET). Besides during the higher rate of infusion pre-ejection period index was decreased. The simple and noninvasive measurement of systolic time intervals is a sensitive index of the inotropic effect of dopamine in children after cardiac surgery.
研究了3和6微克/千克/分钟剂量的多巴胺对16名心脏直视手术后儿童收缩期时间间期（STI）的影响。还评估了基本血流动力学参数——心率、收缩压、舒张压和平均血压。在多巴胺输注的任一速率下，心率均未改变。在较高剂量的多巴胺作用期间，收缩压、舒张压和平均血压显著升高。3和6微克/千克/分钟剂量的多巴胺显著降低了射血前期（PEP）与左心室射血时间（LVET）之间的关系。此外，在较高输注速率期间，射血前期指数降低。收缩期时间间期的简单无创测量是心脏手术后儿童多巴胺变力作用的敏感指标。
