Su Jian, Xiang Quanyong, Lyu Shurong, Pan Xiaoqun, Qin Yu, Yang Jie, Zhou Jinyi, Zhang Yongqing, Wu Ming, Tao Ran
Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China; Email:
Zhonghua Xin Xue Guan Bing Za Zhi. 2015 Jun;43(6):548-53.
To explore the relationship between central obesity and cardiovascular risk factors and their clustering in adults of Jiangsu province.
Multi-stratified clustering sampling method was used to sample 8 400 residents aged 18 years and over from 14 diseases surveillance units in Jiangsu province from October to December 2010. Information was obtained with face-to-face interview, physical examination and laboratory testing. A total of 8 380 residents finished the study protocol and their data were analyzed. Central obesity was defined as waist circumference ≥ 85 cm in males or ≥ 80 cm in females. Following complex weighting of the samples, level and proportion of cardiovascular risk factors in group with different waist circumference were analyzed.
The prevalence of central obesity among adults in Jiangsu province was 46.2%, the proportion of males and females was 46.4% and 46.1%, respectively (P > 0.05). The prevalence of center obesity varied significantly in residents with different age, area, education and occupation (all P < 0.01). The level of systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol and low density lipoprotein cholesterol was also significantly different in residents with different degree of waist circumference (all P < 0.01). The prevalence of hypertension, diabetes, dyslipidemia and clustering of cardiovascular risk factors increased in proportion to increasing waist circumference (all P < 0.05). Multivariate logistic regression analysis showed that the risk of hypertension, diabetes, dyslipidemia and clustering of cardiovascular risk factors was 2.2 (OR = 2.2, 95% CI: 2.0-2.4) and 4.7 (OR = 4.7, 95% CI: 3.9-5.7); 2.1 (OR = 2.1, 95% CI: 1.7-2.5) and 3.8 (OR = 3.8, 95% CI: 3.2-4.5); 2.3 (OR = 2.3, 95% CI: 1.8-2.9) and 4.1 (OR = 4.1, 95% CI: 3.2-5.3); 3.4 (OR = 3.4, 95% CI: 2.9-3.9) and 8.0 (OR = 8.0, 95% CI: 6.2-10.2) fold higher in residents with mild and severe central obesity than residents without central obesity.
The extent of central obesity positively correlates with the prevalence of cardiovascular risk factors and their clustering in adults of Jiangsu province. Comprehensive interventions on obesity serve as an important tool to reduce the cardiovascular risk in adult Jiangshu residents.
探讨江苏省成年人中心性肥胖与心血管危险因素及其聚集情况之间的关系。
采用多阶段整群抽样方法，于2010年10月至12月从江苏省14个疾病监测点抽取8400名18岁及以上居民。通过面对面访谈、体格检查和实验室检测获取信息。共有8380名居民完成研究方案并对其数据进行分析。中心性肥胖定义为男性腰围≥85厘米或女性腰围≥80厘米。在对样本进行复杂加权后，分析不同腰围组中心血管危险因素的水平和比例。
江苏省成年人中心性肥胖患病率为46.2%，男性和女性患病率分别为46.4%和46.1%（P>0.05）。中心性肥胖患病率在不同年龄、地区、教育程度和职业的居民中差异显著（均P<0.01）。不同腰围程度的居民收缩压、舒张压、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平也存在显著差异（均P<0.01）。高血压、糖尿病、血脂异常和心血管危险因素聚集的患病率随腰围增加而升高（均P<0.05）。多因素logistic回归分析显示，轻度和重度中心性肥胖居民患高血压、糖尿病、血脂异常和心血管危险因素聚集的风险分别是无中心性肥胖居民的2.2倍（OR=2.2，95%CI：2.0-2.4）和4.7倍（OR=4.7，95%CI：3.9-5.7）；2.1倍（OR=2.1，95%CI：1.7-2.5）和3.8倍（OR=3.8，95%CI：3.2-4.5）；2.3倍（OR=2.3，95%CI：1.8-2.9）和4.1倍（OR=4.1，95%CI：3.2-5.3）；3.4倍（OR=3.4，95%CI：2.9-3.9）和8.0倍（OR=8.0，95%CI：6.2-10.2）。
江苏省成年人中心性肥胖程度与心血管危险因素及其聚集患病率呈正相关。对肥胖进行综合干预是降低江苏成年居民心血管风险的重要手段。
