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人体红细胞中总镁含量与游离镁含量的相关性。人类白细胞抗原的影响。

Correlation between total and free magnesium levels in human red blood cells. Influence of HLA antigens.

作者信息

Santarromana M, Delepierre M, Féray J C, Franck G, Garay R, Henrotte J G

机构信息

CNRS, Faculté de Pharmacie, Paris, France.

出版信息

Magnes Res. 1989 Dec;2(4):281-3.

PMID:2642072
Abstract

Total and free magnesium contents were determined by atomic absorption spectrophotometry and 31P nuclear magnetic resonance on red blood cells of healthy blood donors of known HLA groups. A statistically significant correlation was found between free and total magnesium contents (r = 0.67, P less than 0.02). The previously described low total magnesium contents in HLA-B35+ subjects were associated with low free Mg2+ contents. Therefore, total and free magnesium and HLA-associated genetic factors are closely related.

摘要

通过原子吸收分光光度法和31P核磁共振法测定了已知HLA组的健康献血者红细胞中的总镁含量和游离镁含量。发现游离镁含量与总镁含量之间存在统计学上的显著相关性(r = 0.67,P < 0.02)。先前描述的HLA - B35+受试者中总镁含量低与游离Mg2+含量低有关。因此,总镁和游离镁与HLA相关的遗传因素密切相关。

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