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马斯喀特阿西卜初级卫生保健中心非甾体抗炎药(NSAIDs)的使用情况:一项临床审计

Non-steroidal Anti-inflammatory Drugs (NSAIDs) Use in Primary Health Care Centers in A'Seeb, Muscat: A Clinical Audit.

作者信息

Al-Shidhani Asma, Al-Rawahi Naama, Al-Rawahi Abdulhakeem

机构信息

North Mawaleh Health Center, Muscat, Oman.

Department of Studies and Research, Oman Medical Specialty Board, Muscat, Oman.

出版信息

Oman Med J. 2015 Sep;30(5):366-71. doi: 10.5001/omj.2015.73.

Abstract

OBJECTIVE

We sought to assess the trend of non-steroidal anti-inflammatory drug (NSAID) use in primary health care institutions located in A'Seeb, a province in the capital city of Oman, Muscat. Additionally, we evaluated the relationship between a physician's years of experience and the number of prescription issued, as well as the presence of risk factors and side effects in the patients who received these prescriptions.

METHOD

A clinical audit was conducted in four primary health care centers in the Muscat region over a one-week period in April 2014. The target population included patients aged 18 years or over who attended one of the four health centers and were prescribed NSAIDs. Overall, 272 patients were recruited by systematic random sampling. The data were collected by two methods: direct face-to-face interviews and evaluations of the patient's electronic medical file. The prescribing doctors were blind to the audit. The collected information included patients demographics, past and current medical history of related comorbidities, NSAID type, dose, duration and indications for use, concomitant warfarin or/and aspirin prescriptions, and co-prescription of gastroprotective agents.

RESULTS

In total, 15% of patients received an NSAID prescription: females were issued more prescriptions than males. The percentage of patients who received an NSAID prescription across the health centers ranged from 9% to 24%. The main reason for prescribing NSAIDs was musculoskeletal problems. The most frequently prescribed NSAID was ibuprofen. Sixteen percent of patients who received an NSAID prescription had a risk factor related to its use. The mean and median duration of the NSAID prescriptions of all types were 5.6 and 5.0 days, respectively. Physicians with a greater number of years experience prescribed more NSAIDs.

CONCLUSION

Our study showed that the number of prescriptions of NSAIDs among various institutes varied, which could reflect the level of awareness concerning NSAID risks among the prescribing doctors. NSAIDs were prescribed for patients with comorbidities and patients with previously documented side effects without considering protective agents. Therefore, we suggest that the use of these medications is controlled, especially in high-risk populations.

摘要

目的

我们试图评估阿曼首都马斯喀特省阿西卜的基层医疗机构中使用非甾体抗炎药(NSAID)的趋势。此外,我们还评估了医生的工作年限与开出的处方数量之间的关系,以及接受这些处方的患者中危险因素和副作用的存在情况。

方法

2014年4月,在马斯喀特地区的四个基层医疗中心进行了为期一周的临床审计。目标人群包括18岁及以上到这四个医疗中心之一就诊并被开具非甾体抗炎药的患者。总体而言,通过系统随机抽样招募了272名患者。数据通过两种方法收集:直接面对面访谈和对患者电子病历的评估。开处方的医生对审计不知情。收集的信息包括患者的人口统计学信息、既往和当前相关合并症的病史、非甾体抗炎药的类型、剂量、用药持续时间和用药指征、同时开具的华法林或/和阿司匹林处方,以及胃保护剂的联合处方。

结果

总共有15%的患者接受了非甾体抗炎药处方:女性开具的处方比男性多。各医疗中心接受非甾体抗炎药处方的患者百分比在9%至%之间。开具非甾体抗炎药的主要原因是肌肉骨骼问题。最常开具的非甾体抗炎药是布洛芬。接受非甾体抗炎药处方的患者中有16%存在与其使用相关的危险因素。所有类型非甾体抗炎药处方的平均和中位用药持续时间分别为5.6天和5.0天。工作年限较长的医生开具的非甾体抗炎药更多。

结论

我们的研究表明,不同机构中非甾体抗炎药的处方数量各不相同,这可能反映了开处方医生对非甾体抗炎药风险的认识水平。非甾体抗炎药被开给患有合并症和先前有副作用记录的患者,而没有考虑使用保护剂。因此,我们建议控制这些药物的使用,尤其是在高危人群中。

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