Adolescent Asthma Pharmacotherapy in a State of Flux.
作者信息
Raissy Hengameh, Blake Kathryn
机构信息
Department of Pediatrics, School of Medicine, University of New Mexico , Alburquerque, New Mexico.
Biomedical Research Department, Nemours Children's Clinic , Jacksonville, Florida.
出版信息
Pediatr Allergy Immunol Pulmonol. 2015 Sep 1;28(3):187-190. doi: 10.1089/ped.2015.0562.
Abstract
Recently, the United States Food and Drug Administration (FDA) elected not to approve a once-daily inhaled corticosteroid/long-acting β2 agonist combination product in 12-17-year-old patients due to lack of sufficient data, despite approval of previous combination products with similar levels of supporting evidence. As the FDA's stance toward adolescent data is changing, the opportunity to learn about their response to asthma medication has now arisen. A review of the relevant issues pertinent to pharmacotherapy of asthma in the 12-17-year-old population is discussed in this review.
摘要
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本文引用的文献
1
Systemic exposure to inhaled beclometasone/formoterol DPI is age and body size dependent.
Respir Med. 2014 Aug;108(8):1108-16. doi: 10.1016/j.rmed.2014.05.007. Epub 2014 Jun 17.
2
The systemic exposure to inhaled beclometasone/formoterol pMDI with valved holding chamber is independent of age and body size.
Pulm Pharmacol Ther. 2015 Feb;30:102-9. doi: 10.1016/j.pupt.2014.04.003. Epub 2014 Apr 16.
3
Effect of inhaled glucocorticoids in childhood on adult height.
N Engl J Med. 2012 Sep 6;367(10):904-12. doi: 10.1056/NEJMoa1203229. Epub 2012 Sep 3.
4
Age and risks of FDA-approved long-acting β₂-adrenergic receptor agonists.
Pediatrics. 2011 Nov;128(5):e1147-54. doi: 10.1542/peds.2010-1720. Epub 2011 Oct 24.
5
Assessing the safety of adding LABAs to inhaled corticosteroids for treating asthma.
N Engl J Med. 2011 Jun 30;364(26):2473-5. doi: 10.1056/NEJMp1104375.
6
Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.
Lancet. 2011 Feb 19;377(9766):650-7. doi: 10.1016/S0140-6736(10)62145-9. Epub 2011 Feb 14.
7
Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids.
N Engl J Med. 2010 Mar 18;362(11):975-85. doi: 10.1056/NEJMoa1001278. Epub 2010 Mar 2.
8
Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma.
Chest. 2006 Jun;129(6):1478-85. doi: 10.1378/chest.129.6.1478.
9
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol.
Chest. 2006 Jan;129(1):15-26. doi: 10.1378/chest.129.1.15.
10
Lung deposition of inhaled drugs increases with age.
Am J Respir Crit Care Med. 2000 Nov;162(5):1819-22. doi: 10.1164/ajrccm.162.5.2002132.
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