Sulla I, Santa M, Marsala J
Neurochirurgische Klinik, Medizinische Fakultät, P.J. Safárik Universität.
Zentralbl Neurochir. 1989;50(3-4):157-8.
The authors give a report on the results obtained in the implantation of autologous nerves in the cerebral hemispheres of rabbits. In a group of five rabbits they implanted a nerve immediately after its removal, in a second equally large group they implanted a nerve only after seven days of preliminary degeneration. After 12 to 14 weeks of the animals with 10 per cent neutral formalin was carried out and the preparations were impregnated according to the Nauta-Gygax method. In the histological sections they only succeeded in discovering individual fibres, which may be the axons of the cerebral cells growing through into the transplanted peripheral nerves. The authors did not see any differences between the immediately implanted nerves and nerves only implanted after a preliminary degeneration. The results obtained require a maximum of caution in the appraisal of the transplantation possibilities in the central nervous system.
作者报告了在兔脑半球植入自体神经所获得的结果。在一组五只兔子中,他们在神经取出后立即进行植入,在另一组同样数量的兔子中,他们仅在经过七天的初步变性后才植入神经。在动物存活12至14周后,用10%的中性福尔马林进行处理,并根据瑙塔 - 吉加克斯方法对标本进行浸染。在组织学切片中,他们仅成功发现了个别纤维,这些纤维可能是长入移植的周围神经的脑细胞轴突。作者未发现立即植入的神经与仅在初步变性后植入的神经之间存在任何差异。所获得的结果在评估中枢神经系统的移植可能性时需要极其谨慎。