Mitchell Richard, Pitts Ryan, Kim Young-Mo, Matava Matthew J
Department of Orthopedic Surgery, Washington University, St. Louis, Missouri, U.S.A.
Department of Orthopedic Surgery, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
Arthroscopy. 2016 Jan;32(1):111-9. doi: 10.1016/j.arthro.2015.07.013. Epub 2015 Oct 1.
To evaluate the time-zero load-to-failure strength of 4 different constructs used to repair medial meniscal root avulsions.
Sixty fresh-frozen cadaveric knees with a mean age of 74 years were used for this study. Each knee was dissected to isolate the attachment of the posterior root of the medial meniscus to the tibial plateau. An Instron machine (Instron, Norwood, MA) with a custom-designed clamp was used to avulse the intact posterior meniscal root in 12 control specimens. An additional 48 specimens were tested after transection of the native meniscal root to evaluate the pullout strength of 4 different repair constructs using No. 0 FiberWire suture (Arthrex, Naples, FL): a single suture (n = 12), a double suture (n = 12), a loop stitch (n = 12), and a locking loop stitch (n = 12). Analysis of variance was used to compare load to failure and stiffness of all 4 groups; pair-wise, between-group differences were also assessed.
Repair failure occurred most commonly by suture pullout in 94% of the specimens in the repair groups. For the controls, failure occurred most commonly at the meniscus-clamp interface. Failure load was highest for the control group (mean, 359.5 ± 168 N), followed in descending order by the locking loop stitch (191.4 ± 45.1 N), loop stitch (119.6 ± 55.0 N), double suture (96.2 ± 51.4 N), and single suture (58.2 ± 29.6 N). The control group was significantly stronger than 3 of the experimental groups (single suture [95% CI, 3.8 to 11.3], double suture [95% CI, 2.1 to 6.4], and loop stitch [95% CI, 2.0 to 4.5]; P < .0001) but not the locking loop stitch (P = .003; 95% CI, 1.2 to 3.2). The locking loop stitch was significantly stronger than the single suture (P < .0001; 95% CI, 2.0 to 5.4) and double suture (P = .003; 95% CI, 1.2 to 2.9). The locking loop stitch was significantly stiffer than the single suture (P < .0001; 95% CI, 3.8 to 20.3), double suture (P < .0001; 95% CI, 2.0 to 9.8), and loop stitch (P = .03; 95% CI, 1.1 to 5.5) but not significantly different from the control group (P = .93; 95% CI, 0.3 to 1.9). Age and gender had no effect on pullout strength.
The results of this study show that the locking loop stitch provided time-zero load-to-failure strength that most closely approximated the strength of the native meniscal root in addition to being significantly stronger and stiffer than 3 other commonly used repair methods. The true strength of the native meniscal root is unknown based on limitations with our testing methodology.
The locking loop stitch exhibited the highest load to failure and stiffness of the 4 fixation methods tested, despite the fact that none of the fixation methods replicated the strength of the intact meniscal root. It is currently unknown what strength of fixation is required for healing of meniscal root repairs.
评估用于修复内侧半月板根部撕脱的4种不同结构的初始负荷至失效强度。
本研究使用了60个平均年龄为74岁的新鲜冷冻尸体膝关节。每个膝关节进行解剖,以分离内侧半月板后根与胫骨平台的附着处。使用带有定制夹具的英斯特朗材料试验机(英斯特朗公司,马萨诸塞州诺伍德)在12个对照标本中撕脱完整的半月板后根。在切断天然半月板根部后,对另外48个标本进行测试,以评估使用0号纤维线缝线( Arthrex公司,佛罗里达州那不勒斯)的4种不同修复结构的拔出强度:单缝线(n = 12)、双缝线(n = 12)、环形缝合法(n = 12)和锁定环形缝合法(n = 12)。采用方差分析比较所有4组的失效负荷和刚度;还评估了组间两两差异。
修复组中94%的标本最常见的修复失败原因是缝线拔出。对于对照组,失败最常发生在半月板-夹具界面。对照组的失效负荷最高(平均,359.5±168 N),其次依次为锁定环形缝合法(191.4±45.1 N)、环形缝合法(119.6±55.0 N)、双缝线(96.2±51.4 N)和单缝线(58.2±29.6 N)。对照组明显强于3个实验组(单缝线[95% CI,3.8至11.3]、双缝线[95% CI,2.1至6.4]和环形缝合法[95% CI,2.0至4.5];P <.0001),但与锁定环形缝合法无显著差异(P =.003;95% CI,1.2至3.2)。锁定环形缝合法明显强于单缝线(P <.0001;95% CI,2.0至5.4)和双缝线(P =.003;95% CI,1.2至2.9)。锁定环形缝合法明显比单缝线(P <.0001;95% CI,3.8至20.3)、双缝线(P <.0001;95% CI,2.0至9.8)和环形缝合法(P =.03;95% CI,1.1至5.5)更硬,但与对照组无显著差异(P =.93;95% CI,0.3至1.9)。年龄和性别对拔出强度无影响。
本研究结果表明,锁定环形缝合法提供的初始负荷至失效强度最接近天然半月板根部的强度,此外还明显强于和硬于其他3种常用的修复方法。基于我们测试方法的局限性,天然半月板根部的真实强度尚不清楚。
在测试的4种固定方法中,锁定环形缝合法表现出最高的失效负荷和刚度,尽管没有一种固定方法能复制完整半月板根部的强度。目前尚不清楚半月板根部修复愈合所需的固定强度是多少。