秀丽隐杆线虫是抗蠕虫药物发现的“灵丹妙药”吗？
Is Caenorhabditis elegans the Magic Bullet for Anthelminthic Drug Discovery?
机构信息
Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.
出版信息
Trends Parasitol. 2015 Oct;31(10):455-456. doi: 10.1016/j.pt.2015.08.004. Epub 2015 Sep 25.
PMID:26422771
Abstract
Recent advances in handling and readout have facilitated high-throughput screens with Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high-throughput anthelminthic drug discovery. Despite challenges, drug discovery using C. elegans offers opportunities that might lead the way to novel anthelminthic drugs.
摘要
近年来，处理和读取技术的进步促进了使用秀丽隐杆线虫进行高通量筛选。一项新的研究表明，秀丽隐杆线虫是一种用于高通量驱虫药物发现的有用工具。尽管存在挑战，但使用秀丽隐杆线虫进行药物发现提供了机会，可能为新型驱虫药物开辟道路。
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