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波兰骨髓捐赠与移植的组织及发展

Organization and Development of Bone Marrow Donation and Transplantation in Poland.

作者信息

Filipiak Jagoda, Dudkiewicz Małgorzata, Czerwiński Jarosław, Kosmala Karolina, Łęczycka Anna, Malanowski Piotr, Żalikowska-Hołoweńko Jolanta, Małkowski Piotr, Danielewicz Roman

机构信息

Department of Surgical and Transplant Nursing, Medical University of Warsaw, Warsaw, Poland.

Polish Transplant Coordinating Center POLTRANSPLANT, Warsaw, Poland.

出版信息

Ann Transplant. 2015 Oct 1;20:588-95. doi: 10.12659/AOT.894285.

DOI:10.12659/AOT.894285
PMID:26423563
Abstract

This paper describes bone marrow donation and transplantation in Poland in terms of its history, current state, and information on the quality control system. Based on data gathered from the informatics systems of the Polish Central Unrelated Potential Bone Marrow Donor and Cord Blood Registry and the Polish transplant registries, as well as World Marrow Donor Association statistics, we performed an overview study to collect and compare numbers on hematopoietic stem cells donations and transplantations in Poland in the years 2010-2014. In the last 5 years, the number of registered potential hematopoietic stem cells donors in Poland increased by more than 4 times, from about 146,000 to over 750,000. During the same period, the number of patients qualified to hematopoietic stem cells transplantation from unrelated donor increased from 557 in 2010 to 817 in 2014. We observed a striking change in the percentage of transplantations performed in Polish centers using material collected from national donors--from 24% to 60%. This shift was also evident in the number of search procedures closed with acceptation of Polish donors--from 27% in 2010 to 58% in 2014. Another consequence of Polish registry growth is the increasing number of donations from Polish donors for international patients. Between 2010 and 2014, the percent of donation for non-national patient increased from 33% to 76%, placing Poland in 6th place in the ranking of the HSC "exporters" worldwide. Growth of transplantation rates involves standardization process, which is a natural way of development for national organizations in the field of HSCT because of its international character.

摘要

本文从历史、现状以及质量控制体系信息等方面描述了波兰的骨髓捐赠与移植情况。基于从波兰中央非血缘潜在骨髓捐赠者和脐血登记处的信息系统、波兰移植登记处收集的数据以及世界骨髓捐赠者协会的统计数据,我们进行了一项概述性研究,以收集和比较2010 - 2014年波兰造血干细胞捐赠与移植的数量。在过去5年中,波兰登记的潜在造血干细胞捐赠者数量增加了4倍多,从约14.6万增至超过75万。同期,符合接受非血缘捐赠者造血干细胞移植条件的患者数量从2010年的557例增至2014年的817例。我们观察到波兰各中心使用从本国捐赠者收集的材料进行移植的比例发生了显著变化——从24%增至60%。这种转变在因接受波兰捐赠者而结束的检索程序数量上也很明显——从2010年的27%增至2014年的58%。波兰登记处发展的另一个结果是波兰捐赠者为国际患者提供的捐赠数量增加。2010年至2014年期间,为非本国患者的捐赠比例从33%增至76%,使波兰在全球造血干细胞“出口国”排名中位列第6。移植率的增长涉及标准化过程,由于造血干细胞移植领域具有国际性质,这对国家组织来说是一种自然的发展方式。

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Organization and Development of Bone Marrow Donation and Transplantation in Poland.波兰骨髓捐赠与移植的组织及发展
Ann Transplant. 2015 Oct 1;20:588-95. doi: 10.12659/AOT.894285.
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Bone marrow donation in Poland: 2021 update, and the impact of the coronavirus disease 2019 pandemic on haematopoietic stem cell transplantation.波兰的骨髓捐赠:2021年最新情况,以及2019冠状病毒病大流行对造血干细胞移植的影响。
Clin Ethics. 2022 Mar;17(1):22-31. doi: 10.1177/14777509211036643.