Hernández C, Sierra I
Bioelimination Laboratory, Radiation Dosimetry Service, CIEMAT, Avda. Complutense 40, 28040 Madrid, Spain
Bioelimination Laboratory, Radiation Dosimetry Service, CIEMAT, Avda. Complutense 40, 28040 Madrid, Spain.
Radiat Prot Dosimetry. 2016 Sep;170(1-4):39-44. doi: 10.1093/rpd/ncv418. Epub 2015 Sep 29.
Two essential technical requirements of ISO 17025 guide for accreditation of testing and calibration laboratories are the validation of methods and the estimation of all sources of uncertainty that may affect the analytical result. Bioelimination Laboratory from Radiation Dosimetry Service of CIEMAT (Spain) uses alpha spectrometry to quantify alpha emitters (Pu, Am, Th, U and Cm isotopes) in urine and faecal samples from workers exposed to internal radiation. Therefore and as a step previous to achieving the ISO 17025 accreditation, the laboratory has performed retrospective studies based on the obtained results in the past few years to validate the analytical method. Uncertainty estimation was done identifying and quantifying all the contributions, and finally the overall combined standard uncertainty was calculated.
ISO 17025检测和校准实验室认可指南的两项基本技术要求是方法验证以及对所有可能影响分析结果的不确定度来源进行评估。西班牙CIEMAT辐射剂量测定服务处的生物消除实验室采用α能谱法对受内照射的工作人员尿液和粪便样本中的α发射体（钚、镅、钍、铀和锔同位素）进行定量分析。因此，作为获得ISO 17025认可的前期步骤，该实验室基于过去几年所获结果开展了回顾性研究，以验证分析方法。通过识别和量化所有不确定度贡献进行不确定度评估，最终计算出合成标准不确定度。
