Department of Endoscopy, Tokyo Womenâs Medical University Yachiyo Medical Center, Yachiyo, Japan.
Department of Gastroenterology, Tokyo Womenâs Medical University Yachiyo Medical Center, Yachiyo, Japan.
Endosc Ultrasound. 2014 Apr;3(Suppl 1):S7.
Aberrant pancreas is used to describe ectopic pancreatic tissue lying outside its normal location with no anatomic or vascular connection to the pancreas proper. Patients with aberrant pancreas are usually asymptomatic, so aberrant pancreas are typically discovered incidentally during endoscopy, surgery, or autopsy. This time, we report a case of gastric aberrant pancreas bleeding was repeated and endoscopic hemostasis was difficult. A 22-year-old man was admitted to a hospital with a complaint of epigastric pain and melena. Upper gastrointestinal endoscopy and endoscopic ultrasonography (EUS) revealed a submucosal tumor with a bleeding ulcer at the anterior wall of the antrum in the stomach, and diagnosed it as an aberrant pancreas. It was hard to stop bleeding by in total 7 times endoscopic hemostasis and anemia was gradually progressed, so partial gastrectomy was performed. This gastric tumor measured 40 mm × 30 mm × 20 mm and had a severe ulcerative change. The pathological diagnosis was aberrant pancreas with Langerhans islet, acinous cells and excretory duct. (Heinrich type) Until December 2013 in Japan, 13 cases of gastric aberrant pancreas with bleeding have been reported and in these, a surgery was done in 11 cases. In gastric aberrant pancreas cases with ulcer formation like this case, endoscopic hemostasis is expected to be difficult, and surgery is necessary. Hence, early accurate diagnosis by EUS is a very important to decide better treatment plan.
异位胰腺是指位于正常胰腺位置以外的胰腺组织,与正常胰腺无解剖或血管联系。患有异位胰腺的患者通常无症状,因此异位胰腺通常是在胃镜、手术或尸检中偶然发现的。此次,我们报告了一例反复发生胃异位胰腺出血且内镜止血困难的病例。一名 22 岁男性因上腹疼痛和黑便就诊。上消化道内镜和内镜超声(EUS)显示胃窦前壁有一个黏膜下肿瘤,伴有出血性溃疡,诊断为异位胰腺。共进行了 7 次内镜止血,出血仍难以止住,且贫血逐渐加重,因此行部分胃切除术。该胃肿瘤大小为 40mm×30mm×20mm,伴有严重的溃疡性改变。病理诊断为异位胰腺,郎格汉斯胰岛、腺泡细胞和外分泌导管(Heinrich 型)。截至 2013 年 12 月,日本共报道了 13 例胃异位胰腺出血病例,其中 11 例行手术治疗。在这种情况下,有溃疡形成的胃异位胰腺病例,预计内镜止血困难,需要手术治疗。因此,EUS 早期准确诊断对于制定更好的治疗方案非常重要。